Framingham Heart Study Bibliography
2012

Ackert-Bicknell CL, Demissie S, Tsaih SW, Beamer WG, Cupples LA, Paigen BJ, Hsu YH, Kiel DP, Karasik D. Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. Bone. May 2012;50(5):1188-1195. (PubMed ID Number: 22306695; PMCID: PMC3322322).

Anderson DE, D'Agostino JM, Bruno AG, Manoharan RK, Bouxsein ML. Regressions for estimating muscle parameters in the thoracic and lumbar trunk for use in musculoskeletal modeling. J Biomech. Jan 3 2012;45(1):66-75. (PubMed ID Number: 22018580; PMCID: PMC3242869).

Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, Gong Y, Hopewell JC, Johnson T, Kleber ME, Langaee TY, Li M, Li YR, Liu K, McDonough CW, Meijs MF, Middelberg RP, Musunuru K, Nelson CP, O'Connell JR, Padmanabhan S, Pankow JS, Pankratz N, Rafelt S, Rajagopalan R, Romaine SP, Schork NJ, Shaffer J, Shen H, Smith EN, Tischfield SE, van der Most PJ, van Vliet-Ostaptchouk JV, Verweij N, Volcik KA, Zhang L, Bailey KR, Bailey KM, Bauer F, Boer JM, Braund PS, Burt A, Burton PR, Buxbaum SG, Chen W, Cooper-Dehoff RM, Cupples LA, deJong JS, Delles C, Duggan D, Fornage M, Furlong CE, Glazer N, Gums JG, Hastie C, Holmes MV, Illig T, Kirkland SA, Kivimaki M, Klein R, Klein BE, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix AZ, Mallela L, Murugesan G, Ordovas J, Ouwehand WH, Post WS, Saxena R, Scharnagl H, Schreiner PJ, Shah T, Shields DC, Shimbo D, Srinivasan SR, Stolk RP, Swerdlow DI, Taylor HA, Jr., Topol EJ, Toskala E, van Pelt JL, van Setten J, Yusuf S, Whittaker JC, Zwinderman AH, Anand SS, Balmforth AJ, Berenson GS, Bezzina CR, Boehm BO, Boerwinkle E, Casas JP, Caulfield MJ, Clarke R, Connell JM, Cruickshanks KJ, Davidson KW, Day IN, de Bakker PI, Doevendans PA, Dominiczak AF, Hall AS, Hartman CA, Hengstenberg C, Hillege HL, Hofker MH, Humphries SE, Jarvik GP, Johnson JA, Kaess BM, Kathiresan S, Koenig W, Lawlor DA, Marz W, Melander O, Mitchell BD, Montgomery GW, Munroe PB, Murray SS, Newhouse SJ, Onland-Moret NC, Poulter N, Psaty B, Redline S, Rich SS, Rotter JI, Schunkert H, Sever P, Shuldiner AR, Silverstein RL, Stanton A, Thorand B, Trip MD, Tsai MY, van der Harst P, van der Schoot E, van der Schouw YT, Verschuren WM, Watkins H, Wilde AA, Wolffenbuttel BH, Whitfield JB, Hovingh GK, Ballantyne CM, Wijmenga C, Reilly MP, Martin NG, Wilson JG, Rader DJ, Samani NJ, Reiner AP, Hegele RA, Kastelein JJ, Hingorani AD, Talmud PJ, Hakonarson H, Elbers CC, Keating BJ, Drenos F. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. Nov 2 2012;91(5):823-838. (PubMed ID Number: 23063622; PMCID: PMC3487124).

Au R, Seshadri S, Knox K, Beiser A, Himali JJ, Cabral HJ, Auerbach S, Green RC, Wolf PA, McKee AC. The Framingham Brain Donation Program: neuropathology along the cognitive continuum. Curr Alzheimer Res. Jul 2012;9(6):673-686. (PubMed ID Number: 22471865).

Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y, Wilson RS, Foroud T, Ott J, Mayeux R, National Institute on Aging Late-Onset Alzheimer's Disease Genetics Society. Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory. Neurology. 2012;78(19):1464-71. doi: 10.1212/WNL.0b013e3182553c48. (PubMed ID Number: 22539578).

Barral S, Fernandez-Cadenas I, Bis JC, Montaner J, Ikram AM, Launer LJ, Fornage M, Schmidt H, Brickman AM, Seshadri S, Mayeux R. No association of ALOX5AP polymorphisms with risk of MRI-defined brain infarcts. Neurobiol Aging. Mar 2012;33(3):629 e621-623. (PubMed ID Number: 22074807; PMCID: PMC3259245).

Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, Jr., Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C. Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts. Am J Hum Genet. Sep 7 2012;91(3):513-519. (PubMed ID Number: 22958901; PMCID: PMC3511985).

Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, Magnusson PK, Surakka I, Ripatti S, Christiansen L, Dalgard C, Folkersen L, Grundberg E, Eriksson P, Kaprio J, Ohm Kyvik K, Pedersen NL, Borecki IB, Province MA, Balkau B, Froguel P, Shuldiner AR, Palmer LJ, Wareham N, Meneton P, Johnson T, Pankow JS, Karasik D, Meigs JB, Kiel DP, Florez JC. Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes. Aug 2012;61(8):2176-2186. (PubMed ID Number: 22698912; PMCID: PMC3402303).

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Jr., Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT, Jr., Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. May 2012;44(5):545-551. (PubMed ID Number: 22504421; PMCID: PMC3427729).

Brautbar A, Pompeii LA, Dehghan A, Ngwa JS, Nambi V, Virani SS, Rivadeneira F, Uitterlinden AG, Hofman A, Witteman JC, Pencina MJ, Folsom AR, Cupples LA, Ballantyne CM, Boerwinkle E. A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. Atherosclerosis. Aug 2012;223(2):421-426. (PubMed ID Number: 22789513).

Britton KA, Pedley A, Massaro JM, Corsini EM, Murabito JM, Hoffmann U, Fox CS. Prevalence, distribution, and risk factor correlates of high thoracic periaortic fat in the Framingham Heart Study. J Am Heart Assoc. Dec 2012;1(6):e004200. (PubMed ID Number: 23316328; PMCID: PMC3540666).

Bruno AG, Anderson DE, D'Agostino J, Bouxsein ML. The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading. J Bone Miner Res. Oct 2012;27(10):2144-2151. (PubMed ID Number: 22589006; PMCID: PMC3431452).

Bukowski R, Chlebowski RT, Thune I, Furberg AS, Hankins GD, Malone FD, D'Alton ME. Birth weight, breast cancer and the potential mediating hormonal environment. PLoS One. 2012;7(7):e40199. (PubMed ID Number: 22815728; PMCID: PMC3398929).

Butler AM, Yin X, Evans DS, Nalls MA, Smith EN, Tanaka T, Li G, Buxbaum SG, Whitsel EA, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen W, Deo R, Ellinor PT, Heckbert SR, Heiss G, Hsueh WC, Keating BJ, Kerr KF, Li Y, Limacher MC, Liu Y, Lubitz SA, Marciante KD, Mehra R, Meng YA, Newman AB, Newton-Cheh C, North KE, Palmer CD, Psaty BM, Quibrera PM, Redline S, Reiner AP, Rotter JI, Schnabel RB, Schork NJ, Singleton AB, Smith JG, Soliman EZ, Srinivasan SR, Zhang ZM, Zonderman AB, Ferrucci L, Murray SS, Evans MK, Sotoodehnia N, Magnani JW, Avery CL. Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circulation Cardiovascular genetics. 2012;5(6):639-46. Epub 2012/11/10. doi: 10.1161/circgenetics.112.963991. (PubMed ID Number: 23139255; PMCID: PMC3560365).

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Boger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tonjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimaki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nothlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Volker U, Volzke H, Kovacs P, Stumvoll M, Magi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kahonen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Kramer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Kottgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. Dec 15 2012;21(24):5329-5343. (PubMed ID Number: 22962313).

Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q. Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study. PLoS One. 2012;7(12):e51589. (PubMed ID Number: 23284720; PMCID: PMC3524237).

Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ. Metabolite profiling identifies pathways associated with metabolic risk in humans. Circulation. May 8 2012;125(18):2222-2231. (PubMed ID Number: 22496159; PMCID: PMC3376658).

Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM. Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. Jan 2012;220(1):145-150. (PubMed ID Number: 22093724; PMCID: PMC3277804).

Cheng S, Xanthakis V, Sullivan LM, Vasan RS. Blood pressure tracking over the adult life course: patterns and correlates in the Framingham Heart Study. Hypertension. Dec 2012;60(6):1393-1399. (PubMed ID Number: 23108660; PMCID: PMC3499677).

Chiang CW, Liu CT, Lettre G, Lange LA, Jorgensen NW, Keating BJ, Vedantam S, Nock NL, Franceschini N, Reiner AP, Demerath EW, Boerwinkle E, Rotter JI, Wilson JG, North KE, Papanicolaou GJ, Cupples LA, Genetic Investigation of ATC, Murabito JM, Hirschhorn JN. Ultraconserved Elements in the Human Genome: Association and Transmission Analyses of Highly Constrained Single-Nucleotide Polymorphisms. Genetics. 2012;192(1):253-66. doi: 10.1534/genetics.112.141945. (PubMed ID Number: 22714408; PMCID: PMC3430540).

Cho I, Chang HJ, Sung JM, Pencina MJ, Lin FY, Dunning AM, Achenbach S, Al-Mallah M, Berman DS, Budoff MJ, Callister TQ, Chow BJ, Delago A, Hadamitzky M, Hausleiter J, Maffei E, Cademartiri F, Kaufmann P, Shaw LJ, Raff GL, Chinnaiyan KM, Villines TC, Cheng V, Nasir K, Gomez M, Min JK, Investigators C. Coronary computed tomographic angiography and risk of all-cause mortality and nonfatal myocardial infarction in subjects without chest pain syndrome from the CONFIRM Registry (coronary CT angiography evaluation for clinical outcomes: an international multicenter registry). Circulation. 2012;126(3):304-13. doi: 10.1161/CIRCULATIONAHA.111.081380. (PubMed ID Number: 22685117).

Chu AY, Guilianini F, Grallert H, Dupuis J, Ballantyne CM, Barratt BJ, Nyberg F, Chasman DI, Ridker PM. Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. Circulation Cardiovascular genetics. 2012;5(6):676-85. Epub 2012/11/03. doi: 10.1161/CIRCGENETICS.112.963314. (PubMed ID Number: 23118302).

Chuang ML, Gona P, Hautvast GL, Salton CJ, Blease SJ, Yeon SB, Breeuwer M, O'Donnell CJ, Manning WJ. Correlation of trabeculae and papillary muscles with clinical and cardiac characteristics and impact on CMR measures of LV anatomy and function. JACC Cardiovascular imaging. 2012;5(11):1115-23. doi: 10.1016/j.jcmg.2012.05.015. (PubMed ID Number: 23153911; PMCID: PMC3502069).

Chuang ML, Gona P, Salton CJ, Yeon SB, Kissinger KV, Blease SJ, Levy D, O'Donnell CJ, Manning WJ. Usefulness of the left ventricular myocardial contraction fraction in healthy men and women to predict cardiovascular morbidity and mortality. Am J Cardiol. 2012;109(10):1454-8. Epub 28 Feb 2012. doi: 10.1016/j.amjcard.2012.01.357. (PubMed ID Number: 22381161; PMCID: PMC3742100).

Chuang ML, Gona P, Hautvast GL, Salton CJ, Blease SJ, Yeon SB, Breeuwer M, O'Donnell CJ, Manning WJ. Correlation of trabeculae and papillary muscles with clinical and cardiac characteristics and impact on cmr measures of LV anatomy and function. JACC Cardiovasc Imaging. Nov 2012;5(11):1115-1123. (PubMed ID Number: 23153911; PMCID: PMC3502069).

Chuang ML, Massaro JM, Levitzky YS, Fox CS, Manders ES, Hoffmann U, O'Donnell CJ. Prevalence and distribution of abdominal aortic calcium by gender and age group in a community-based cohort (from the Framingham Heart Study). Am J Cardiol. Sep 15 2012;110(6):891-896. (PubMed ID Number: 22727181; PMCID: PMC3432173).

Chun S, Tu JV, Wijeysundera HC, Austin PC, Wang X, Levy D, Lee DS. Lifetime analysis of hospitalizations and survival of patients newly admitted with heart failure. Circ Heart Fail. 2012;5(4):414-21. doi: 10.1161/CIRCHEARTFAILURE.111.964791. (PubMed ID Number: 22556322).

Coglianese EE, Larson MG, Vasan RS, Ho JE, Ghorbani A, McCabe EL, Cheng S, Fradley MG, Kretschman D, Gao W, O'Connor G, Wang TJ, Januzzi JL. Distribution and clinical correlates of the interleukin receptor family member soluble ST2 in the Framingham Heart Study. Clin Chem. Dec 2012;58(12):1673-1681. (PubMed ID Number: 23065477; PMCID: PMC3557515).

Coglianese EE, Qureshi MM, Vasan RS, Wang TJ, Moore LL. Usefulness of the blood hematocrit level to predict development of heart failure in a community. Am J Cardiol. Jan 15 2012;109(2):241-245. (PubMed ID Number: 21996141).

Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimaki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikainen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren O, Lorentzon M, Maggio M, Markus MR, Mellstrom D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stockl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kahonen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Jarvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012;8(7):e1002805. (PubMed ID Number: 22829776; PMCID: PMC3400553).

Cusano NE, Kiel DP, Demissie S, Karasik D, Adrienne Cupples L, Corella D, Gao Q, Richardson K, Yiannakouris N, Ordovas JM. A Polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study. Calcif Tissue Int. Feb 2012;90(2):96-107. (PubMed ID Number: 22210160).

D'Agostino RB, Sr. Cardiovascular risk estimation in 2012: lessons learned and applicability to the HIV population. J Infect Dis. Jun 2012;205 Suppl 3:S362-367. (PubMed ID Number: 22577209; PMCID: PMC3349294).

Dallmeier D, Larson MG, Vasan RS, Keaney JF, Jr., Fontes JD, Meigs JB, Fox CS, Benjamin EJ. Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study. Diabetol Metab Syndr. 2012;4(1):28. (PubMed ID Number: 22716219; PMCID: PMC3547735).

Dallmeier D, Larson MG, Wang N, Fontes JD, Benjamin EJ, Fox CS. Addition of inflammatory biomarkers did not improve diabetes prediction in the community: the Framingham Heart Study. J Am Heart Assoc. Aug 2012;1(4):e000869. (PubMed ID Number: 23130155; PMCID: PMC3487343).

Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikainen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kahonen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Bohringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimaki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segre AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bostrom KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jorgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proenca C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparso T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Magi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proenca C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Bottcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martinez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orru M, 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Farina EK, Kiel DP, Roubenoff R, Schaefer EJ, Cupples LA, Tucker KL. Plasma phosphatidylcholine concentrations of polyunsaturated fatty acids are differentially associated with hip bone mineral density and hip fracture in older adults: the Framingham Osteoporosis Study. J Bone Miner Res. May 2012;27(5):1222-1230. (PubMed ID Number: 22392875; PMCID: PMC3565380).

Fedorowski A, Franceschini N, Brody J, Liu C, Verwoert GC, Boerwinkle E, Couper D, Rice KM, Rotter JI, Mattace-Raso F, Uitterlinden A, Hofman A, Almgren P, Sjogren M, Hedblad B, Larson MG, Newton-Cheh C, Wang TJ, Rose KM, Psaty BM, Levy D, Witteman J, Melander O. Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.Eur Heart J. Sep 2012;33(18):2331-2341. (PubMed ID Number: 22504314; PMCID: PMC3442958).

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Foroud T, Koller DL, Lai D, Sauerbeck L, Anderson C, Ko N, Deka R, Mosley TH, Fornage M, Woo D, Moomaw CJ, Hornung R, Huston J, Meissner I, Bailey-Wilson JE, Langefeld C, Rouleau G, Connolly ES, Worrall BB, Kleindorfer D, Flaherty ML, Martini S, Mackey J, De Los Rios La Rosa F, Brown RD, Jr., Broderick JP, Investigators FIAS. Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk. Stroke. 2012;43(11):2846-52. doi: 10.1161/STROKEAHA.112.656397. (PubMed ID Number: 22961961; PMCID: PMC3752852).

Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ, Gudnason V, Harris TB, Cupples LA, Borecki IB. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012;8(5):e1002695. (PubMed ID Number: 22589738; PMCID: PMC3349734).

Fox CS, Matsushita K, Woodward M, Bilo HJ, Chalmers J, Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP, Nelson RG.Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet. Nov 10 2012;380(9854):1662-1673. (PubMed ID Number: 23013602).

Fox CS, White CC, Lohman K, Heard-Costa N, Cohen P, Zhang Y, Johnson AD, Emilsson V, Liu CT, Chen YD, Taylor KD, Allison M, Budoff M, Rotter JI, Carr JJ, Hoffmann U, Ding J, Cupples LA, Liu Y. Genome-wide association of pericardial fat identifies a unique locus for ectopic fat. PLoS Genet. 2012;8(5):e1002705. (PubMed ID Number: 22589742; PMCID: PMC3349742).

Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF, Jr., Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, Marz W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. Jan 2012;33(2):238-251. (PubMed ID Number: 22003152; PMCID: PMC3258449).

Granada M, Wilk JB, Tuzova M, Strachan DP, Weidinger S, Albrecht E, Gieger C, Heinrich J, Himes BE, Hunninghake GM, Celedon JC, Weiss ST, Cruikshank WW, Farrer LA, Center DM, O'Connor GT. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. The Journal of allergy and clinical immunology. 2012;129(3):840-5 e21. Epub 2011/11/15. doi: 10.1016/j.jaci.2011.09.029. (PubMed ID Number: 22075330; PMCID: PMC3293994).

Hameed F, Hunter DJ, Rainville J, Li L, Suri P. Prevalence of anatomic impediments to interlaminar lumbar epidural steroid injection. Arch Phys Med Rehabil. Feb 2012;93(2):339-343. (PubMed ID Number: 22289247; PMCID: PMC3567928).

Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Glaser S, Marchini J, Kraft P, Wareham NJ, Volzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet. 2012;8(12):e1003098. Epub 2013/01/04. doi: 10.1371/journal.pgen.1003098. (PubMed ID Number: 23284291; PMCID: PMC3527213).

Hannan MT, Broe KE, Cupples LA, Dufour AB, Rockwell M, Kiel DP. Height loss predicts subsequent hip fracture in men and women of the Framingham Study. J Bone Miner Res. 2012;27(1):146-52. Epub 2011/11/11. doi: 10.1002/jbmr.557. (PubMed ID Number: 22072590; PMCID: PMC3647683).

Haring R, Xanthakis V, Coviello A, Sullivan L, Bhasin S, Wallaschofski H, Murabito JM, Vasan RS. Clinical correlates of sex steroids and gonadotropins in men over the late adulthood: the Framingham Heart Study. Int J Androl. Dec 2012;35(6):775-782. (PubMed ID Number: 22640232; PMCID: PMC3434249).

Harris WS, Pottala JV, Lacey SM, Vasan RS, Larson MG, Robins SJ. Clinical correlates and heritability of erythrocyte eicosapentaenoic and docosahexaenoic acid content in the Framingham Heart Study.Atherosclerosis. Dec 2012;225(2):425-431. (PubMed ID Number: 22727409).

Harris WS, Pottala JV, Vasan RS, Larson MG, Robins SJ. Changes in erythrocyte membrane trans and marine fatty acids between 1999 and 2006 in older Americans. J Nutr. Jul 2012;142(7):1297-1303. (PubMed ID Number: 22623386; PMCID: PMC3374668).

Hautvast GL, Salton CJ, Chuang ML, Breeuwer M, O'Donnell CJ, Manning WJ. Accurate computer-aided quantification of left ventricular parameters: Experience in 1555 cardiac magnetic resonance studies from the Framingham Heart Study. Magn Reson Med. 2012;67(5):1478-86. Epub 2011/10/25. doi: 10.1002/mrm.23127. (PubMed ID Number: 22021128; PMCID: PMC3267005).

He C, Chasman DI, Dreyfus J, Hwang SJ, Ruiter R, Sanna S, Buring JE, Fernandez-Rhodes L, Franceschini N, Hankinson SE, Hofman A, Lunetta KL, Palmieri G, Porcu E, Rivadeneira F, Rose LM, Splansky GL, Stolk L, Uitterlinden AG, Chanock SJ, Crisponi L, Demerath EW, Murabito JM, Ridker PM, Stricker BH, Hunter DJ.Reproductive aging-associated common genetic variants and the risk of breast cancer. Breast Cancer Res. 2012;14(2):R54. (PubMed ID Number: 22433456; PMCID: PMC3446388).

Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. Oct 2 2012;60(14):1249-1256. (PubMed ID Number: 22939561; PMCID: PMC3512095).

Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ. Clinical and genetic correlates of growth differentiation factor 15 in the community. Clin Chem. 2012;58(11):1582-91. Epub 2012/09/22. doi: 10.1373/clinchem.2012.190322. (PubMed ID Number: 22997280; PMCID: PMC4150608).

Hsieh YC, Seshadri S, Chung WT, Hsieh FI, Hsu YH, Lin HJ, Tseng HP, Lien LM, Bai CH, Hu CJ, Jeng JS, Tang SC, Chen CI, Yu CC, Chiou HY, Formosa Stroke Genetic Consortium. Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan. Journal of biomedical science. 2012;19:1. doi: 10.1186/1423-0127-19-1. (PubMed ID Number: 22212150; PMCID: PMC3269363).

Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A, Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH, Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ, Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B, Ohrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R, Franco-Cereceda A, Syvanen AC, Goodall AH, Yanek LR, Cushman M, Muller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH, Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB, Consortium D, Kathiresan S, Reilly MP, Consortium CA, Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL, Watkins H, Consortium CD, Spector TD, Becker LC, Tracy RP, Marz W, Uitterlinden AG, Eriksson P, Cambien F, Consortium C, Morange PE, Koenig W, Soranzo N, van der Harst P, Liu Y, O'Donnell CJ, Hamsten A. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012;120(24):4873-81. doi: 10.1182/blood-2012-06-436188. (PubMed ID Number: 22990020; PMCID: PMC3520624).

Ibrahim-Verbaas CA, Zorkoltseva IV, Amin N, Schuur M, Coppus AM, Isaacs A, Aulchenko YS, Breteler MM, Ikram MA, Axenovich TI, Verbeek MM, van Swieten JC, Oostra BA, van Duijn CM. Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Abeta-40 levels to presenilin 2. Human genetics. 2012;131(12):1869-76. doi: 10.1007/s00439-012-1210-2. (PubMed ID Number: 22872014).

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Kaess BM, Pedley A, Massaro JM, Larson MG, Corsini E, Hoffmann U, Smith HM, Sawyer DB, Vasan RS, Fox CS. Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study. J Clin Endocrinol Metab. Mar 2012;97(3):987-994. (PubMed ID Number: 22170711; PMCID: PMC3319207).

Kaess BM, Pedley A, Massaro JM, Murabito J, Hoffmann U, Fox CS. The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk.Diabetologia. Oct 2012;55(10):2622-2630. (PubMed ID Number: 22898763).

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Karasik D, Cheung CL, Zhou Y, Cupples LA, Kiel DP, Demissie S. Genome-wide association of an integrated osteoporosis-related phenotype: is there evidence for pleiotropic genes? J Bone Miner Res. Feb 2012;27(2):319-330. (PubMed ID Number: 22072498; PMCID: PMC3290743).

Kao PF, Banigan MG, Vanderburg CR, McKee AC, Polgar PR, Seshadri S, Delalle I. Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol. 2012;71(7):654-64. doi: 10.1097/NEN.0b013e31825d06b7. (PubMed ID Number: 22710966; PMCID: PMC3398703).

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Kim YM, Demissie S, Genant HK, Cheng X, Yu W, Samelson EJ, Kiel DP, Bouxsein ML. Identification of prevalent vertebral fractures using CT lateral scout views: a comparison of semi-automated quantitative vertebral morphometry and radiologist semi-quantitative grading. Osteoporos Int. 2012;23(3):1007-16. Epub 2011/09/20. doi: 10.1007/s00198-011-1774-z. (PubMed ID Number: 21927924; PMCID: PMC3584446).

Kimokoti RW, Gona P, Zhu L, Newby PK, Millen BE, Brown LS, D'Agostino RB, Fung TT. Dietary patterns of women are associated with incident abdominal obesity but not metabolic syndrome. J Nutr. Sep 2012;142(9):1720-1727. (PubMed ID Number: 22833658; PMCID: PMC3417833).

Kimokoti RW, Newby PK, Gona P, Zhu L, Campbell WR, D'Agostino RB, Millen BE. Stability of the Framingham Nutritional Risk Score and its component nutrients over 8 years: the Framingham Nutrition Studies. Eur J Clin Nutr. Mar 2012;66(3):336-344. (PubMed ID Number: 21970940).

Kottgen A, Yang Q, Shimmin LC, Tin A, Schaeffer C, Coresh J, Liu X, Rampoldi L, Hwang SJ, Boerwinkle E, Hixson JE, Kao WH, Fox CS. Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One. 2012;7(5):e38311. (PubMed ID Number: 22693617; PMCID: PMC3365030).

Lessov-Schlaggar CN, Hardin J, DeCarli C, Krasnow RE, Reed T, Wolf PA, Swan GE, Carmelli D. Longitudinal genetic analysis of brain volumes in normal elderly male twins. Neurobiol Aging. 2012;33(4):636-44. doi: 10.1016/j.neurobiolaging.2010.06.002. (PubMed ID Number: 20630620; PMCID: PMC2970700).

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Li J, Guo YF, Pei Y, Deng HW. The impact of imputation on meta-analysis of genome-wide association studies. PLoS One. 2012;7(4):e34486. (PubMed ID Number: 22496814; PMCID: PMC3320624).

Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. Oct 2012;60(4):949-956. (PubMed ID Number: 22949535).

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Liu CT, Karasik D, Zhou Y, Hsu YH, Genant HK, Broe KE, Lang TF, Samelson EJ, Demissie S, Bouxsein ML, Cupples LA, Kiel DP. Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. J Bone Miner Res. 2012;27(4):954-8. Epub 2012/01/10. doi: 10.1002/jbmr.1537. (PubMed ID Number: 22222934; PMCID: PMC3375687).

Liu E, McKeown NM, Pittas AG, Meigs JB, Economos CD, Booth SL, Jacques PF. Predicted 25-hydroxyvitamin D score and change in fasting plasma glucose in the Framingham offspring study. Eur J Clin Nutr. 2012;66(1):139-41. doi: 10.1038/ejcn.2011.181. (PubMed ID Number: 22009071; PMCID: PMC3796766).

Lluis-Ganella C, Subirana I, Lucas G, Tomas M, Munoz D, Senti M, Salas E, Sala J, Ramos R, Ordovas JM, Marrugat J, Elosua R. Assessment of the value of a genetic risk score in improving the estimation of coronary risk. Atherosclerosis. Jun 2012;222(2):456-463. (PubMed ID Number: 22521901).

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Magnani JW, Moser CB, Murabito JM, Nelson KP, Fontes JD, Lubitz SA, Sullivan LM, Ellinor PT, Benjamin EJ. Age of natural menopause and atrial fibrillation: the Framingham Heart Study. Am Heart J. Apr 2012;163(4):729-734. (PubMed ID Number: 22520541; PMCID: PMC3334861).

Magnani JW, Newton-Cheh C, O'Donnell CJ, Levy D. Development and application of a longitudinal electrocardiogram repository: the Framingham Heart Study. J Electrocardiol. Nov-Dec 2012;45(6):673-676. (PubMed ID Number: 22832152; PMCID: PMC3483375).

Maillard P, Seshadri S, Beiser A, Himali JJ, Au R, Fletcher E, Carmichael O, Wolf PA, DeCarli C. Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study. Lancet Neurol. Dec 2012;11(12):1039-1047. (PubMed ID Number: 23122892 PMCID: PMC3510663).

Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Bottcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbaton-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G, Hamsten A, Hansson O, Harris TB, Hayward C, Heath S, Hercberg S, Hicks AA, Hingorani A, Hofman A, Hui J, Hung J, Jarvelin MR, Jhun MA, Johnson PC, Jukema JW, Jula A, Kao WH, Kaprio J, Kardia SL, Keinanen-Kiukaanniemi S, Kivimaki M, Kolcic I, Kovacs P, Kumari M, Kuusisto J, Kyvik KO, Laakso M, Lakka T, Lannfelt L, Lathrop GM, Launer LJ, Leander K, Li G, Lind L, Lindstrom J, Lobbens S, Loos RJ, Luan J, Lyssenko V, Magi R, Magnusson PK, Marmot M, Meneton P, Mohlke KL, Mooser V, Morken MA, Miljkovic I, Narisu N, O'Connell J, Ong KK, Oostra BA, Palmer LJ, Palotie A, Pankow JS, Peden JF, Pedersen NL, Pehlic M, Peltonen L, Penninx B, Pericic M, Perola M, Perusse L, Peyser PA, Polasek O, Pramstaller PP, Province MA, Raikkonen K, Rauramaa R, Rehnberg E, Rice K, Rotter JI, Rudan I, Ruokonen A, Saaristo T, Sabater-Lleal M, Salomaa V, Savage DB, Saxena R, Schwarz P, Seedorf U, Sennblad B, Serrano-Rios M, Shuldiner AR, Sijbrands EJ, Siscovick DS, Smit JH, Small KS, Smith NL, Smith AV, Stancakova A, Stirrups K, Stumvoll M, Sun YV, Swift AJ, Tonjes A, Tuomilehto J, Trompet S, Uitterlinden AG, Uusitupa M, Vikstrom M, Vitart V, Vohl MC, Voight BF, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Wheeler E, Widen E, Wild SH, Willems SM, Willemsen G, Wilson JF, Witteman JC, Wright AF, Yaghootkar H, Zelenika D, Zemunik T, Zgaga L, Wareham NJ, McCarthy MI, Barroso I, Watanabe RM, Florez JC, Dupuis J, Meigs JB, Langenberg C. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.Nat Genet. Jun 2012;44(6):659-669. (PubMed ID Number: 22581228).

Marjamaa A, Oikarinen L, Porthan K, Ripatti S, Peloso G, Noseworthy PA, Viitasalo M, Nieminen MS, Toivonen L, Kontula K, Peltonen L, Havulinna AS, Jula A, O'Donnell CJ, Newton-Cheh C, Perola M, Salomaa V. A common variant near the KCNJ2 gene is associated with T-peak to T-end interval. Heart Rhythm. Jul 2012;9(7):1099-1103. (PubMed ID Number: 22342860).

McManus DD, Lyass A, Ingelsson E, Massaro JM, Meigs JB, Aragam J, Benjamin EJ, Vasan RS. Relations of circulating resistin and adiponectin and cardiac structure and function: the Framingham Offspring Study. Obesity (Silver Spring). Sep 2012;20(9):1882-1886. (PubMed ID Number: 21350435).

McManus DD, Rienstra M, Benjamin EJ. An update on the prognosis of patients with atrial fibrillation. Circulation. 2012;126(10):e143-6. doi: 10.1161/​CIRCULATIONAHA.112.129759. (PubMed ID Number: 22949543; PMCID: PMC3678907).

Mitchell BD, Lee WJ, Tolea MI, Shields K, Ashktorab Z, Magder LS, Ryan KA, Pollin TI, McArdle PF, Shuldiner AR, Schaffer AA. Living the good life? Mortality and hospital utilization patterns in the Old Order Amish. PloS one. 2012;7(12):e51560. doi: 10.1371/journal.pone.0051560. (PubMed ID Number: 23284714; PMCID: 3526600).

Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Ikram MA, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. Feb 1 2012;5(1):81-90. (PubMed ID Number: 22068335; PMCID: PMC3288392).

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Murabito JM, Yuan R, Lunetta KL. The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals. J Gerontol A Biol Sci Med Sci. 2012;67(5):470-9. doi: 10.1093/gerona/gls089. (PubMed ID Number: 22499766; PMCID: PMC3326242).

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O'Seaghdha CM, Hwang SJ, Vasan RS, Larson MG, Hoffmann U, Wang TJ, Fox CS. Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the Framingham Heart Study. BMC Endocr Disord. 2012;12:3. (PubMed ID Number: 22475205; PMCID: PMC3352034).

O'Seaghdha CM, Lyass A, Massaro JM, Meigs JB, Coresh J, D'Agostino RB, Sr., Astor BC, Fox CS. A risk score for chronic kidney disease in the general population. Am J Med. Mar 2012;125(3):270-277. (PubMed ID Number: 22340925; PMCID: PMC3285426).

O'Seaghdha CM, Yang Q, Wu H, Hwang SJ, Fox CS. Performance of a genetic risk score for CKD stage 3 in the general population. Am J Kidney Dis. Jan 2012;59(1):19-24. (PubMed ID Number: 21995970; PMCID: PMC3242901).

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Pencina MJ. Caution is needed in the interpretation of added value of biomarkers analyzed in matched case control studies. Clin Chem. 2012;58(8):1176-8. doi: 10.1373/clinchem.2012.188383. (PubMed ID Number: 22730448).

Pencina MJ, D'Agostino RB, Sr., Demler OV. Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models. Stat Med. Jan 30 2012;31(2):101-113. (PubMed ID Number: 22147389; PMCID: PMC3341978).

Pencina MJ, D'Agostino RB, Demler OV, Janssens AC, Greenland P. Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution". Am J Epidemiol. Sep 15 2012;176(6):492-494. (PubMed ID Number: 22875757; PMCID: PMC3530352).

Pencina MJ, D'Agostino RB, Pencina KM, Janssens AC, Greenland P. Interpreting incremental value of markers added to risk prediction models. Am J Epidemiol. Sep 15 2012;176(6):473-481. (PubMed ID Number: 22875755; PMCID: PMC3530349).

Pencina MJ, D'Agostino RB, Sr., Song L. Quantifying discrimination of Framingham risk functions with different survival C statistics. Stat Med. Jul 10 2012;31(15):1543-1553. (PubMed ID Number: 22344892).

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Piccini JP, Hammill BG, Sinner MF, Jensen PN, Hernandez AF, Heckbert SR, Benjamin EJ, Curtis LH. Incidence and prevalence of atrial fibrillation and associated mortality among Medicare beneficiaries, 1993-2007. Circulation-Cardiovascular Quality and Outcomes. 2012;5(1):85-93. doi: 10.1161/CIRCOUTCOMES.111.962688. (PubMed ID Number: 22235070; PMCID: PMC3332107).

Piccini JP, Sinner MF, Greiner MA, Hammill BG, Fontes JD, Daubert JP, Ellinor PT, Hernandez AF, Walkey AJ, Heckbert SR, Benjamin EJ, Curtis LH. Outcomes of Medicare beneficiaries undergoing catheter ablation for atrial fibrillation. Circulation. 2012;126(18):2200-7. Epub 9/26/12. doi: 10.1161/CIRCULATIONAHA.112.109330. (PubMed ID Number: 23019293; PMCID: PMC3500836).

Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S. Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study. Circulation. May 1 2012;125(17):2100-2107. (PubMed ID Number: 22456473; PMCID: PMC3427730).

Polak JF, Meisner A, Pencina MJ, Wolf PA, D'Agostino RB. Variations in common carotid artery intima-media thickness during the cardiac cycle: implications for cardiovascular risk assessment. J Am Soc Echocardiogr. Sep 2012;25(9):1023-1028. (PubMed ID Number: 22721828; PMCID: PMC3544292).

Polak JF, Pencina MJ. Measuring carotid artery intima-media thickness: simplicity versus complexity?J Am Soc Echocardiogr. Jan 2012;25(1):101-104. (PubMed ID Number: 22183023).

Prushik SG, Farber A, Gona P, Shrader P, Pencina MJ, D'Agostino RB, Sr., Murabito JM. Parental intermittent claudication as risk factor for claudication in adults. Am J Cardiol. Mar 1 2012;109(5):736-741. (PubMed ID Number: 22154319; PMCID: PMC3288128).

Rao M, Mottl AK, Cole SA, Umans JG, Freedman BI, Bowden DW, Langefeld CD, Fox CS, Yang Q, Cupples A, Iyengar SK, Hunt SC, Trikalinos TA. Meta-analysis of genome-wide linkage scans for renal function traits. Nephrol Dial Transplant. Feb 2012;27(2):647-656. (PubMed ID Number: 21622988; PMCID: PMC3275782).

Refaat MM, Lubitz SA, Makino S, Islam Z, Frangiskakis JM, Mehdi H, Gutmann R, Zhang ML, Bloom HL, MacRae CA, Dudley SC, Shalaby AA, Weiss R, McNamara DM, London B, Ellinor PT. Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm. 2012;9(3):390-6. Epub 2011/10/19. doi: 10.1016/j.hrthm.2011.10.016. (PubMed ID Number: 22004663; PMCID: PMC3516872).

Rienstra M, Lubitz SA, Mahida S, Magnani JW, Fontes JD, Sinner MF, Van Gelder IC, Ellinor PT, Benjamin EJ. Symptoms and functional status of patients with atrial fibrillation: state of the art and future research opportunities. Circulation. Jun 12 2012;125(23):2933-2943. (PubMed ID Number: 22689930; PMCID: PMC3402179).

Rienstra M, McManus DD, Benjamin EJ. Novel risk factors for atrial fibrillation: useful for risk prediction and clinical decision making? Circulation. 2012;125(20):e941-6. Epub 2012/05/23. doi: 10.1161/CIRCULATIONAHA.112.112920. (PubMed ID Number: 22615425; PMCID: PMC3725394).

Rienstra M, Sun JX, Lubitz SA, Frankel DS, Vasan RS, Levy D, Magnani JW, Sullivan LM, Meigs JB, Ellinor PT, Benjamin EJ. Plasma resistin, adiponectin, and risk of incident atrial fibrillation: the Framingham Offspring Study. Am Heart J. Jan 2012;163(1):119-124 e111. (PubMed ID Number: 22172445; PMCID: PMC3375331).

Rienstra M, Sun JX, Magnani JW, Sinner MF, Lubitz SA, Sullivan LM, Ellinor PT, Benjamin EJ. White blood cell count and risk of incident atrial fibrillation (from the Framingham Heart Study). Am J Cardiol. Feb 15 2012;109(4):533-537. (PubMed ID Number: 22100030; PMCID: PMC3270118).

Roberts LD, Souza AL, Gerszten RE, Clish CB. Targeted metabolomics. Curr Protoc Mol Biol. Apr 2012;Chapter 30:Unit 30 32 31-24. (PubMed ID Number: 22470063; PMCID: PMC3334318).

Roemer FW, Guermazi A, Niu J, Zhang Y, Mohr A, Felson DT. Prevalence of magnetic resonance imaging-defined atrophic and hypertrophic phenotypes of knee osteoarthritis in a population-based cohort. Arthritis Rheum. Feb 2012;64(2):429-437. (PubMed ID Number: 22094921; PMCID: PMC3268883).

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Romero JR, Preis SR, Beiser AS, DeCarli C, Lee DY, Viswanathan A, Benjamin EJ, Fontes J, Au R, Pikula A, Wang J, Kase CS, Wolf PA, Irrizary MC, Seshadri S. Lipoprotein phospholipase A2 and cerebral microbleeds in the Framingham Heart Study. Stroke. Nov 2012;43(11):3091-3094. (PubMed ID Number: 22961963; PMCID: PMC3544291).

Rutter MK, Massaro JM, Hoffmann U, O'Donnell CJ, Fox CS. Fasting glucose, obesity, and coronary artery calcification in community-based people without diabetes. Diabetes Care. Sep 2012;35(9):1944-1950. (PubMed ID Number: 22773705; PMCID: PMC3425010).

Sakakeeny L, Roubenoff R, Obin M, Fontes JD, Benjamin EJ, Bujanover Y, Jacques PF, Selhub J. Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. adults. J Nutr. Jul 2012;142(7):1280-1285. (PubMed ID Number: 22623384; PMCID: PMC3374666).

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