Dr. L. Adrienne Cupples received her doctorate in mathematical statistics from Boston University. She is Professor of Biostatistics and Epidemiology at Boston University School of Public Health. Dr. Cupples has been actively involved in research with the Framingham Heart Study for more than 25 years.

Dr. Cupples has published numerous refereed articles in journals such as the New England Journal, the Journal of the American Medical Association, Neurology and the American Journal of Human Genetics. Her research interests focus on biostatistical methods for epidemiologic studies, survival data analysis, and genetic epidemiology. Dr. Cupples has extensive experience in statistical analyses of observational and family studies. She has been a primary statistician collaborating on projects studying heart disease (the Framingham Heart Study), Alzheimer's disease (MIRAGE) and Huntington's disease (Center without Walls). Her publications in the Framingham Heart Study have included substantive research on risk factors for sudden coronary death, the relation of dietary factors and development of coronary heart disease and methodological papers on statistical methods used in the Framingham Study for dealing with time-dependent covariates. Over the past 15 years Dr. Cupples has increasingly become involved in evaluating the genetic etiology of cardiovascular disease in the Framingham Study, focusing primarily on lipid, glycemic, bone and subclinical cardiovascular traits. Her professional association memberships include the American Statistical Association, the Society for Epidemiologic Research, the American Society of Human Genetics, and the International Genetic Epidemiology Society.