Christopher J. O'Donnell, MD, MPH
Associate Director, Framingham Heart Study
Senior Advisor to the Director of NHLBI for Genome Research
Chief, Cardiovascular Epidemiology and Human Genomics Branch, NHLBI Division of Intramural Research
Associate Clinical Professor, Harvard Medical School
73 Mt. Wayte Avenue
Framingham, Massachusetts 01702
Dr. O'Donnell received his undergraduate degree, a Bachelor of Arts in biochemistry magna cum laude, from Brown University, his Doctor of Medicine from Harvard Medical School, and his Master's degree in Public Health from the Harvard School of Public Health. He completed a residency in internal medicine and a clinical fellowship in cardiology at the Massachusetts General Hospital. He is currently on staff as a practicing cardiologist in the Cardiology Division, Department of Medicine, Massachusetts General Hospital, and he is an Associate Clinical Professor of Medicine at Harvard Medical School. In 2010, he completed the NIH Executive Leadership Program.
Dr. O'Donnell, a cardiologist and genetic epidemiologist, is an internationally renowned expert in clinical and population cardiovascular genomics. He joined NHLBI as a medical officer at NHLBI's landmark Framingham Heart Study in 1996 and became Associate Director of the Framingham Heart Study in 2002. He also serves as co-chair of the Framingham Genetic Steering Committee. He is a tenured senior investigator in the NHLBI Division of Intramural Research (DIR), where he serves as Chief of the Cardiovascular Epidemiology and Human Genomics Branch of the NHLBI Division of Intramural Research, and the Associate Director of the Framingham Heart Study. In recent years, he has led major research programs, serving as the Scientific Director of the Framingham Heart Study SHARe genome research program as well as a leader in several large cardiovascular genomics consortia, including the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium and the NHLBI Exome Sequencing Program. Dr. O'Donnell's major research has focused on the discovery of genetic and environmental determinants of clinical and subclinical atherosclerotic cardiovascular disease, the leading cause of death in men and women. His research team has led the discovery of multiple genes underlying subclinical atherosclerosis and clinical coronary artery disease. He has published more than 400 peer-reviewed articles and chapters, including many reports in high impact journals such as the New England Journal of Medicine, the Journal of the American Medical Association, Nature, and Nature Genetics.
Dr. O'Donnell is an elected fellow of the American College of Cardiology and the American Heart Association (AHA). He is an elected member of the American Society for Clinical Investigation and he previously served as an associate member of the Broad Institute of Harvard and Massachusetts Institute of Technology. He is the immediate past chair of the council for Epidemiology and Prevention of the American Heart Association and was also past chair of that organization's Statistics Committee. He has also served as a member or chair on numerous other Committees and Working Groups of the NHLBI, NIH, and the AHA. Dr. O'Donnell is a recipient of several Awards of Merit from the NHLBI and the NIH for his research achievements and his direction of epidemiology and genomics programs.