FHS Bibliography – 2014
Framingham Heart Study Bibliography – 2014
Abdullah A, Amin FA, Stoelwinder J, Tanamas SK, Wolfe R, Barendregt J, Peeters A. Estimating the risk of cardiovascular disease using an obese-years metric. BMJ open. 2014;4(9):e005629. doi: 10.1136/bmjopen-2014-005629. (PubMed ID Number: 25231490; PMCID: PMC4166414).
Abraham TM, Massaro JM, Hoffmann U, Yanovski JA, Fox CS. Metabolic characterization of adults with binge eating in the general population: The Framingham Heart Study. Obesity (Silver Spring). 2014;22(11):2441-9. doi: 10.1002/oby.20867. (PubMed ID Number: 25136837; PMCID: PMC4224974).
Alonso A, Yin X, Roetker NS, Magnani JW, Kronmal RA, Ellinor PT, Chen LY, Lubitz SA, McClelland RL, McManus DD, Soliman EZ, Huxley RR, Nazarian S, Szklo M, Heckbert SR, Benjamin EJ. Blood lipids and the incidence of atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis and the Framingham Heart Study. Journal of the American Heart Association. 2014;3(5):e001211. doi: 10.1161/JAHA.114.001211. (PubMed ID Number: 25292185; PMCID: PMC4323837).
Alvey NJ, Pedley A, Rosenquist KJ, Massaro JM, O’Donnell CJ, Hoffmann U, Fox CS. Association of fat density with subclinical atherosclerosis. Journal of the American Heart Association. 2014;3(4). doi: 10.1161/JAHA.114.000788. (PubMed ID Number: 25169793; PMCID: PMC4310364).
Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ. Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014;35(42):2972-9. doi: 10.1093/eurheartj/ehu153. (PubMed ID Number: 24742886; PMCID: PMC4223610).
Anderson DE, Demissie S, Allaire BT, Bruno AG, Kopperdahl DL, Keaveny TM, Kiel DP, Bouxsein ML. The associations between QCT-based vertebral bone measurements and prevalent vertebral fractures depend on the spinal locations of both bone measurement and fracture. Osteoporos Int. 2014;25(2):559-66. doi: 10.1007/s00198-013-2452-0. (PubMed ID Number: 23925651; PMCID: PMC3946739).
Andersson C, Lyass A, Vasan RS, Massaro JM, D’Agostino RB, Sr., Robins SJ. Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study. Am Heart J. 2014;168(6):878-83 e1. doi: 10.1016/j.ahj.2014.08.007. (PubMed ID Number: 25458651).
Andersson C, Vasan RS. Epidemiology of Heart Failure with Preserved Ejection Fraction. Heart Fail Clin. 2014;10(3):377-88. doi: 10.1016/j.hfc.2014.04.003. (PubMed ID Number: 24975902; PMCID: PMC4084609).
Andersson C, Vasan RS. Is there a role for coronary artery calcium scoring for management of asymptomatic patients at risk for coronary artery disease?: Clinical risk scores are sufficient to define primary prevention treatment strategies among asymptomatic patients. Circ Cardiovasc Imaging. 2014;7(2):390-7; discussion 7. doi: 10.1161/CIRCIMAGING.113.000470. (PubMed ID Number: 24642921; PMCID: PMC4154564).
Andersson C, Vasan RS. Compiling the complement of genes implicated in coronary artery disease. Circulation Cardiovascular genetics. 2014;7(6):738-40. doi: 10.1161/CIRCGENETICS.114.000909. (PubMed ID Number: 25516622).
Arcaya M, Glymour MM, Chakrabarti P, Christakis NA, Kawachi I, Subramanian SV. Effects of proximate foreclosed properties on individuals’ systolic blood pressure in Massachusetts, 1987 to 2008. Circulation. 2014;129(22):2262-8. doi: 10.1161/CIRCULATIONAHA.113.006205. (PubMed ID Number: 24891622; PMCID: PMC4098719).
Arcaya M, Glymour MM, Christakis NA, Kawachi I, Subramanian SV. Individual and spousal unemployment as predictors of smoking and drinking behavior. Soc Sci Med. 2014;110:89-95. doi: 10.1016/j.socscimed.2014.03.034. (PubMed ID Number: 24727666; PMCID: PMC4043205).
Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dorr M, Muller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikainen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai AT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J, Consortium CA, Consortium C, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polasek O, Wright AF, Griffin M, Daly MJ, Dcct/Edic, Arnar DO, Holm H, Thorsteinsdottir U, e MC, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O’Donnell CJ, Yin X, Bobbo M, D’Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jockel KH, Kalsch H, Nothen MM, Consortium H, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, Prucha H, Sinner MF, Waldenberger M, de Boer RA, Franke L, van der Vleuten PA, Beckmann BM, Martens E, Bardai A, Hofman N, Wilde AA, Behr ER, Dalageorgou C, Giudicessi JR, Medeiros-Domingo A, Barc J, Kyndt F, Probst V, Ghidoni A, Insolia R, Hamilton RM, Scherer SW, Brandimarto J, Margulies K, Moravec CE, Greco MF, Fuchsberger C, O’Connell JR, Lee WK, Watt GC, Campbell H, Wild SH, El Mokhtari NE, Frey N, Asselbergs FW, Mateo Leach I, Navis G, van den Berg MP, van Veldhuisen DJ, Kellis M, Krijthe BP, Franco OH, Hofman A, Kors JA, Uitterlinden AG, Witteman JC, Kedenko L, Lamina C, Oostra BA, Abecasis GR, Lakatta EG, Mulas A, Orru M, Schlessinger D, Uda M, Markus MR, Volker U, Snieder H, Spector TD, Arnlov J, Lind L, Sundstrom J, Syvanen AC, Kivimaki M, Kahonen M, Mononen N, Raitakari OT, Viikari JS, Adamkova V, Kiechl S, Brion M, Nicolaides AN, Paulweber B, Haerting J, Dominiczak AF, Nyberg F, Whincup PH, Hingorani AD, Schott JJ, Bezzina CR, Ingelsson E, Ferrucci L, Gasparini P, Wilson JF, Rudan I, Franke A, Muhleisen TW, Pramstaller PP, Lehtimaki TJ, Paterson AD, Parsa A, Liu Y, van Duijn CM, Siscovick DS, Gudnason V, Jamshidi Y, Salomaa V, Felix SB, Sanna S, Ritchie MD, Stricker BH, Stefansson K, Boyer LA, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kaab S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature genetics. 2014;46(8):826-36. doi: 10.1038/ng.3014. (PubMed ID Number: 24952745; PMCID: PMC4124521).
Barnes DE, Beiser AS, Lee A, Langa KM, Koyama A, Preis SR, Neuhaus J, McCammon RJ, Yaffe K, Seshadri S, Haan MN, Weir DR. Development and validation of a brief dementia screening indicator for primary care. Alzheimer’s & dementia: the journal of the Alzheimer’s Association. 2014;10(6):656-65 e1. doi: 10.1016/j.jalz.2013.11.006. (PubMed ID Number: 24491321; PMCID: PMC4119094).
Basson J, Sung YJ, Schwander K, Kume R, Simino J, de Las Fuentes L, Rao D. Gene-education interactions identify novel blood pressure Loci in the Framingham Heart Study. Am J Hypertens. 2014;27(3):431-44. doi: 10.1093/ajh/hpt283. (PubMed ID Number: 24473254; PMCID: PMC3915746).
Baumert J, Huang J, McKnight B, Sabater-Lleal M, Steri M, Chu AY, Trompet S, Lopez LM, Fornage M, Teumer A, Tang W, Rudnicka AR, Malarstig A, Hottenga J, Kavousi M, Lahti J, Tanaka T, Hayward C, Huffman JE, Morange P, Rose LM, Basu S, Rumley A, Stott DJ, Buckley BM, de Craen AJ, Sanna S, Masala M, Biffar R, Homuth G, Silveira A, Sennblad B, Goel A, Watkins H, Muller-Nurasyid M, Ruckerl R, Taylor K, Chen M, de Geus EJ, Hofman A, Witteman JC, de Maat MP, Palotie A, Davies G, Siscovick DS, Kolcic I, Wild SH, Song J, McArdle WL, Ford I, Sattar N, Schlessinger D, Grotevendt A, Franzosi MG, Illig T, Waldenberger M, Lumley T, Tofler GH, Willemsen G, Uitterlinden AG, Rivadeneira F, Raikkonen K, Chasman DI, Folsom AR, Lowe GD, Westendorp RG, Slagboom PE, Cucca F, Wallaschofski H, Strawbridge RJ, Seedorf U, Koenig W, Bis JC, Mukamal KJ, van Dongen J, Widen E, Franco OH, Starr JM, Liu K, Ferrucci L, Polasek O, Wilson JF, Oudot-Mellakh T, Campbell H, Navarro P, Bandinelli S, Eriksson J, Boomsma DI, Dehghan A, Clarke R, Hamsten A, Boerwinkle E, Jukema JW, Naitza S, Ridker PM, Volzke H, Deary IJ, Reiner AP, Tregouet D, O’Donnell CJ, Strachan DP, Peters A, Smith NL. No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects. PloS one. 2014;9(12):e111156. doi: 10.1371/journal.pone.0111156. (PubMed ID Number: 25551457; PMCID: PMC4281156).
Beaulieu LM, Lin E, Mick E, Koupenova M, Weinberg EO, Kramer CD, Genco CA, Tanriverdi K, Larson MG, Benjamin EJ, Freedman JE. Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arterioscler Thromb Vasc Biol. 2014;34(3):552-64. doi: 10.1161/ATVBAHA.113.302700. (PubMed ID Number: 24458711; PMCID: PMC4070375).
Ben-Shlomo Y, Spears M, Boustred C, May M, Anderson SG, Benjamin EJ, Boutouyrie P, Cameron J, Chen CH, Cruickshank JK, Hwang SJ, Lakatta EG, Laurent S, Maldonado J, Mitchell GF, Najjar SS, Newman AB, Ohishi M, Pannier B, Pereira T, Vasan RS, Shokawa T, Sutton-Tyrell K, Verbeke F, Wang KL, Webb DJ, Willum Hansen T, Zoungas S, McEniery CM, Cockcroft JR, Wilkinson IB. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol. 2014;63(7):636-46. doi: 10.1016/j.jacc.2013.09.063. (PubMed ID Number: 24239664; PMCID: PMC4401072).
Berry SD, McLean RR, Hannan MT, Cupples LA, Kiel DP. Changes in bone mineral density may predict the risk of fracture differently in older adults according to fall history. Journal of the American Geriatrics Society. 2014;62(12):2345-9. doi: 10.1111/jgs.13127. (PubMed ID Number: 25438807; PMCID: PMC4356210).
Bihlmeyer NA, Brody JA, Smith A, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza S, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M, Liu Y, Faul JD, Kardia S, Zhao W, Ferrucci L, Allerhand M, Liewald DC, Redmond P, Starr JM, De Jager PL, Evans DA, Direk N, Ikram M, Uitterlinden A, Homuth G, Lorbeer R, Grabe HJ, Launer L, Murabito JM, Singleton AB, Weir DR, Bandinelli S, Deary IJ, Bennett DA, Tiemeier H, Kocher T, Lumley T, Arking DE. Genetic diversity is a predictor of mortality in humans. BMC Genet. 2014;15(1):1274. doi: 10.1186/s12863-014-0159-7. (PubMed ID Number: 25543667; PMCID: PMC4301661).
Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR, Jr., Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, Lumley T, Gupta M, Wolf PA, van Duijn C, Gibbs RA, Mosley TH, Longstreth WT, Jr., Boerwinkle E, Seshadri S, Fornage M. Associations of NINJ2 Sequence Variants with Incident Ischemic Stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) Consortium. PloS one. 2014;9(6):e99798. doi: 10.1371/journal.pone.0099798. (PubMed ID Number: 24959832; PMCID: PMC4069013).
Bis JC, White CC, Franceschini N, Brody J, Zhang X, Muzny D, Santibanez J, Gibbs R, Liu X, Lin H, Boerwinkle E, Psaty BM, North KE, Cupples LA, O’Donnell CJ, Group CSAW. Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation Cardiovascular genetics. 2014;7(3):359-64. doi: 10.1161/CIRCGENETICS.113.000116. (PubMed ID Number: 24951662; PMCID: PMC4112104).
Boada M, Antunez C, Ramirez-Lorca R, DeStefano AL, Gonzalez-Perez A, Gayan J, Lopez-Arrieta J, Ikram MA, Hernandez I, Marin J, Galan JJ, Bis JC, Mauleon A, Rosende-Roca M, Moreno-Rey C, Gudnasson V, Moron FJ, Velasco J, Carrasco JM, Alegret M, Espinosa A, Vinyes G, Lafuente A, Vargas L, Fitzpatrick AL, Alzheimer’s Disease Neuroimaging I, Launer LJ, Saez ME, Vazquez E, Becker JT, Lopez OL, Serrano-Rios M, Tarraga L, van Duijn CM, Real LM, Seshadri S, Ruiz A. ATP5H/KCTD2 locus is associated with Alzheimer’s disease risk. Molecular psychiatry. 2014;19(6):682-7. doi: 10.1038/mp.2013.86. (PubMed ID Number: 23857120; PMCID: PMC4031637).
Boardman JD, Domingue BW, Blalock CL, Haberstick BC, Harris KM, McQueen MB. Is the gene-environment interaction paradigm relevant to genome-wide studies? The case of education and body mass index. Demography. 2014;51(1):119-39. doi: 10.1007/s13524-013-0259-4. (PubMed ID Number: 24281739; PMCID: PMC4035460).
Bruno AG, Broe KE, Zhang X, Samelson EJ, Meng CA, Manoharan R, D’Agostino J, Cupples LA, Kiel DP, Bouxsein ML. Vertebral size, bone density, and strength in men and women matched for age and areal spine BMD. J Bone Miner Res. 2014;29(3):562-9. doi: 10.1002/jbmr.2067. (PubMed ID Number: 23955966; PMCID: PMC4149904).
Burke GM, Wang N, Blease S, Levy D, Magnani JW. Assessment of reproducibility–automated and digital caliper ECG measurement in the Framingham Heart Study. J Electrocardiol. 2014;47(3):288-93. doi: 10.1016/j.jelectrocard.2014.01.004. (PubMed ID Number: 24792985; PMCID: PMC4010803).
Burkart KM, Manichaikul A, Wilk JB, Ahmed FS, Burke GL, Enright P, Hansel NN, Haynes D, Heckbert SR, Hoffman EA, Kaufman JD, Kurai J, Loehr L, London SJ, Meng Y, O’Connor GT, Oelsner E, Petrini M, Pottinger TD, Powell CA, Redline S, Rotter JI, Smith LJ, Soler Artigas M, Tobin MD, Tsai MY, Watson K, White W, Young TR, Rich SS, Barr RG. APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema. The European respiratory journal. 2014;43(4):1003-17. doi: 10.1183/09031936.00147612. (PubMed ID Number: 23900982; PMCID: PMC4041087).
Chen H, Lumley T, Brody J, Heard-Costa NL, Fox CS, Cupples LA, Dupuis J. Sequence kernel association test for survival traits. Genet Epidemiol. 2014;38(3):191-7. doi: 10.1002/gepi.21791. (PubMed ID Number: 24464521; PMCID: PMC4158946).
Chen H, Meigs JB, Dupuis J. Incorporating Gene-Environment Interaction in Testing for Association with Rare Genetic Variants. Hum Hered. 2014;78(2):81-90. doi: 10.1159/000363347. (PubMed ID Number: 25060534; PMCID: PMC4169076).
Chen Z, Yi GY, Wu C. Marginal analysis of longitudinal ordinal data with misclassification in both response and covariates. Biometrical journal Biometrische Zeitschrift. 2014;56(1):69-85. doi: 10.1002/bimj.201200195. (PubMed ID Number: 24123126).
Cheng S, Enserro D, Xanthakis V, Sullivan LM, Murabito JM, Benjamin EJ, Polak JF, O’Donnell CJ, Wolf PA, O’Connor GT, Keaney JF, Vasan RS. Association of exhaled carbon monoxide with subclinical cardiovascular disease and their conjoint impact on the incidence of cardiovascular outcomes. Eur Heart J. 2014;35(42):2980-7. doi: 10.1093/eurheartj/ehu052. (PubMed ID Number: 24574370; PMCID: PMC4271053).
Christakis NA, Fowler JH. Friendship and natural selection. Proc Natl Acad Sci U S A. 2014;111 Suppl 3:10796-801. doi: 10.1073/pnas.1400825111. (PubMed ID Number: 25024208; PMCID: PMC4113922).
Chuang ML, Gona P, Hautvast GL, Salton CJ, Breeuwer M, O’Donnell CJ, Manning WJ. CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis: The Framingham Heart Study. J Magn Reson Imaging. 2014;39(4):895-900. doi: 10.1002/jmri.24239. (PubMed ID Number: 24123369; PMCID: PMC3961548).
Chuang ML, Gona P, Oyama-Manabe N, Manders ES, Salton CJ, Hoffmann U, Manning WJ, O’Donnell CJ. Risk factor differences in calcified and noncalcified aortic plaque: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2014;34(7):1580-6. doi: 10.1161/ATVBAHA.114.303600. (PubMed ID Number: 24833796; PMCID: PMC4099001).
Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, Gillum RF, Kim YH, McAnulty JH, Jr., Zheng ZJ, Forouzanfar MH, Naghavi M, Mensah GA, Ezzati M, Murray CJ. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation. 2014;129(8):837-47. doi: 10.1161/CIRCULATIONAHA.113.005119. (PubMed ID Number: 24345399; PMCID: PMC4151302).
Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HC, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WH, Liu CT, McKnight B, Muzny D, Pankow JS, Reid JG, White CC, Johnson AD, Wong TY, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Sladek R, Meigs JB. Association of Levels of Fasting Glucose and Insulin With Rare Variants at the Chromosome 11p11.2-MADD Locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation Cardiovascular genetics. 2014;7(3):374-82. doi: 10.1161/CIRCGENETICS.113.000169. (PubMed ID Number: 24951664; PMCID: PMC4066205).
Dam TT, Peters KW, Fragala M, Cawthon PM, Harris TB, McLean R, Shardell M, Alley DE, Kenny A, Ferrucci L, Guralnik J, Kiel DP, Kritchevsky S, Vassileva MT, Studenski S. An evidence-based comparison of operational criteria for the presence of sarcopenia. J Gerontol A Biol Sci Med Sci. 2014;69(5):584-90. doi: 10.1093/gerona/glu013. (PubMed ID Number: 24737561; PMCID: PMC3991139).
Das K, Daniels MJ. A semiparametric approach to simultaneous covariance estimation for bivariate sparse longitudinal data. Biometrics. 2014;70(1):33-43. doi: 10.1111/biom.12133. (PubMed ID Number: 24400941; PMCID: PMC3954444).
Dashti HS, Shea MK, Smith CE, Tanaka T, Hruby A, Richardson K, Wang TJ, Nalls MA, Guo X, Liu Y, Yao J, Li D, Johnson WC, Benjamin EJ, Kritchevsky SB, Siscovick DS, Ordovas JM, Booth SL. Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. Am J Clin Nutr. 2014;100(6):1462-9. doi: 10.3945/ajcn.114.093146. (PubMed ID Number: 25411281; PMCID: PMC4232014).
Delling FN, Gona P, Larson MG, Lehman B, Manning WJ, Levine RA, Benjamin EJ, Vasan RS. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J Am Soc Echocardiogr. 2014;27(1):17-23. doi: 10.1016/j.echo.2013.09.015. (PubMed ID Number: 24206636; PMCID: PMC4239996).
Delling FN, Vasan RS. Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. Circulation. 2014;129(21):2158-70. doi: 10.1161/CIRCULATIONAHA.113.006702. (PubMed ID Number: 24867995; PMCID: PMC4052751).
Deo RC, Musso G, Tasan M, Tang P, Poon A, Yuan C, Felix JF, Vasan RS, Beroukhim R, De Marco T, Kwok PY, MacRae CA, Roth FP. Prioritizing causal disease genes using unbiased genomic features.Genome biology. 2014;15(12):534. doi: 10.1186/s13059-014-0534-8. (PubMed ID Number: 25633252; PMCID: PMC4279789).
Dichgans M, Malik R, Konig IR, Rosand J, Clarke R, Gretarsdottir S, Thorleifsson G, Mitchell BD, Assimes TL, Levi C, O’Donnell CJ, Fornage M, Thorsteinsdottir U, Psaty BM, Hengstenberg C, Seshadri S, Erdmann J, Bis JC, Peters A, Boncoraglio GB, Marz W, Meschia JF, Kathiresan S, Ikram MA, McPherson R, Stefansson K, Sudlow C, Reilly MP, Thompson JR, Sharma P, Hopewell JC, Chambers JC, Watkins H, Rothwell PM, Roberts R, Markus HS, Samani NJ, Farrall M, Schunkert H, Consortium M, Consortium CA, Consortium CD, International Stroke Genetics C. Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke. 2014;45(1):24-36. doi: 10.1161/STROKEAHA.113.002707. (PubMed ID Number: 24262325; PMCID: PMC4112102).
Domingue BW, Fletcher J, Conley D, Boardman JD. Genetic and educational assortative mating among US adults. Proc Natl Acad Sci U S A. 2014;111(22):7996-8000. doi: 10.1073/pnas.1321426111. (PubMed ID Number: 24843128; PMCID: PMC4050565).
Downer B, Zanjani F, Fardo DW. The Relationship Between Midlife and Late Life Alcohol Consumption, APOE e4 and the Decline in Learning and Memory Among Older Adults. Alcohol and alcoholism. 2014;49(1):17-22. doi: 10.1093/alcalc/agt144. (PubMed ID Number: 24049153; PMCID: PMC3865814).
Dufour AB, Casey VA, Golightly YM, Hannan MT. Characteristics associated with hallux valgus in a population-based foot study of older adults. Arthritis Care Res (Hoboken). 2014;66(12):1880-6. doi: 10.1002/acr.22391. (PubMed ID Number: 24965070).
Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, Larkin E, Martin LW, Bis JC, Auer P, Ramachandran VS, Gabriel SB, Willis MS, Pankow JS, Papanicolaou GJ, Rotter JI, Ballantyne CM, Gross MD, Lettre G, Wilson JG, Peters U, Koenig W, Tracy RP, Redline S, Reiner AP, Benjamin EJ, Lange LA. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Human genetics. 2014;133(8):985-95. doi: 10.1007/s00439-014-1439-z. (PubMed ID Number: 24643644; PMCID: PMC4104766).
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M, United Kingdom Brain Expression C, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernandez I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fievet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossu P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-Garcia A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O’Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Jr., Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nothen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J, Cardiovascular Health S. Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease. PloS one. 2014;9(6):e94661. doi: 10.1371/journal.pone.0094661. (PubMed ID Number: 24922517; PMCID: PMC4055488).
Fowkes FG, Murray GD, Butcher I, Folsom AR, Hirsch AT, Couper DJ, Debacker G, Kornitzer M, Newman AB, Sutton-Tyrrell KC, Cushman M, Lee AJ, Price JF, D’Agostino RB, Sr., Murabito JM, Norman P, Masaki KH, Bouter LM, Heine RJ, Stehouwer CD, McDermott MM, Stoffers HE, Knottnerus JA, Ogren M, Hedblad B, Koenig W, Meisinger C, Cauley JA, Franco O, Hunink MG, Hofman A, Witteman JC, Criqui MH, Langer RD, Hiatt WR, Hamman RF, Ankle Brachial Index C. Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events. European journal of preventive cardiology. 2014;21(3):310-20. doi: 10.1177/2047487313516564. (PubMed ID Number: 24367001).
Fox CS, Pencina MJ, Heard-Costa NL, Shrader P, Jaquish C, O’Donnell CJ, Vasan RS, Cupples LA, D’Agostino RB. Trends in the association of parental history of obesity over 60 years. Obesity (Silver Spring). 2014;22(3):919-24. doi: 10.1002/oby.20564. (PubMed ID Number: 23836774; PMCID: PMC3887126).
Friedman DJ, Wang N, Meigs JB, Hoffmann U, Massaro JM, Fox CS, Magnani JW. Pericardial Fat is Associated With Atrial Conduction: The Framingham Heart Study. Journal of the American Heart Association. 2014;3(2):e000477. doi: 10.1161/JAHA.113.000477. (PubMed ID Number: 24595189; PMCID: PMC4187474).
Frost L, Benjamin EJ, Fenger-Gron M, Pedersen A, Tjonneland A, Overvad K. Body fat, body fat distribution, lean body mass and atrial fibrillation and flutter. A Danish cohort study. Obesity (Silver Spring). 2014;22(6):1546-52. doi: 10.1002/oby.20706. (PubMed ID Number: 24436019; PMCID: PMC4169701).
Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C, Global Blood Pressure Genetics C, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014;95(1):49-65. doi: 10.1016/j.ajhg.2014.06.002. (PubMed ID Number: 24975945; PMCID: PMC4085637).
Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D’Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE. Biomarkers of Cardiovascular Stress and Subclinical Atherosclerosis in the Community. Clin Chem. 2014;60(11):1402-8. doi: 10.1373/clinchem.2014.227116. (PubMed ID Number: 25237063; PMCID: PMC4376479).
Gordon AS, Tabor HK, Johnson AD, Snively BM, Assimes TL, Auer PL, Ioannidis JP, Peters U, Robinson JG, Sucheston LE, Wang D, Sotoodehnia N, Rotter JI, Psaty BM, Jackson RD, Herrington DM, O’Donnell CJ, Reiner AP, Rich SS, Rieder MJ, Bamshad MJ, Nickerson DA, Project NGES. Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset. Hum Mol Genet. 2014;23(8):1957-63. doi: 10.1093/hmg/ddt588. (PubMed ID Number: 24282029; PMCID: PMC3959810).
Gordon LB, Massaro J, D’Agostino RB, Sr., Campbell SE, Brazier J, Brown WT, Kleinman ME, Kieran MW, Progeria Clinical Trials C. Impact of farnesylation inhibitors on survival in hutchinson-gilford progeria syndrome. Circulation. 2014;130(1):27-34. doi: 10.1161/CIRCULATIONAHA.113.008285. (PubMed ID Number: 24795390; PMCID: PMC4082404).
Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimaki T, Lumley T, Marciante KD, Perusse L, Psaty BM, Robbins J, Tranah GJ, Vink JM, Wilk JB, Stafford JM, Bellis C, Biffar R, Bouchard C, Cade B, Curhan GC, Eriksson JG, Ewert R, Ferrucci L, Fulop T, Gehrman PR, Goodloe R, Harris TB, Heath AC, Hernandez D, Hofman A, Hottenga JJ, Hunter DJ, Jensen MK, Johnson AD, Kahonen M, Kao L, Kraft P, Larkin EK, Lauderdale DS, Luik AI, Medici M, Montgomery GW, Palotie A, Patel SR, Pistis G, Porcu E, Quaye L, Raitakari O, Redline S, Rimm EB, Rotter JI, Smith AV, Spector TD, Teumer A, Uitterlinden AG, Vohl MC, Widen E, Willemsen G, Young T, Zhang X, Liu Y, Blangero J, Boomsma DI, Gudnason V, Hu F, Mangino M, Martin NG, O’Connor GT, Stone KL, Tanaka T, Viikari J, Gharib SA, Punjabi NM, Raikkonen K, Volzke H, Mignot E, Tiemeier H. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular psychiatry. 2014. doi: 10.1038/mp.2014.133. (PubMed ID Number: 25469926; PMCID: PMC4430294).
Govindaraju DR, Pencina KM, Raj DS, Massaro JM, Carnes BA, D’Agostino RB. A systems analysis of age-related changes in some cardiac aging traits. Biogerontology. 2014;15(2):139-52. doi: 10.1007/s10522-013-9486-8. (PubMed ID Number: 24337960).
Green AK, Jacques PF, Rogers G, Fox CS, Meigs JB, McKeown NM. Sugar-sweetened beverages and prevalence of the metabolically abnormal phenotype in the Framingham Heart Study. Obesity (Silver Spring). 2014;22(5):E157-63. doi: 10.1002/oby.20724. (PubMed ID Number: 24550031; PMCID: PMC4139414).
He H, Zhang L, Li J, Wang YP, Zhang JG, Shen J, Guo YF, Deng HW. Integrative analysis of GWASs, human protein interaction, and gene expression identified gene modules associated with BMDs. J Clin Endocrinol Metab. 2014;99(11):E2392-9. doi: 10.1210/jc.2014-2563. (PubMed ID Number: 25119315; PMCID: PMC4223444).
Haring R, Friedrich N, Volzke H, Vasan RS, Felix SB, Dorr M, Meyer zu Schwabedissen HE, Nauck M, Wallaschofski H. Positive association of serum prolactin concentrations with all-cause and cardiovascular mortality. Eur Heart J. 2014;35(18):1215-21. Epub 7/26/12. doi: 10.1093/eurheartj/ehs233. (PubMed ID Number: 22843444).
Ho JE, Larson MG, Ghorbani A, Cheng S, Coglianese EE, Vasan RS, Wang TJ. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. Journal of the American Heart Association. 2014;3(3):e000668. doi: 10.1161/JAHA.113.000668. (PubMed ID Number: 24811610; PMCID: PMC4309047).
Ho JE, Yin X, Levy D, Vasan RS, Magnani JW, Ellinor PT, McManus DD, Lubitz SA, Larson MG, Benjamin EJ. Galectin 3 and incident atrial fibrillation in the community. Am Heart J. 2014;167(5):729-34 e1. doi: 10.1016/j.ahj.2014.02.009. (PubMed ID Number: 24766984; PMCID: PMC4007212).
Holliday EG, Traylor M, Malik R, Bevan S, Maguire J, Koblar SA, Sturm J, Hankey GJ, Oldmeadow C, McEvoy M, Sudlow C, Rothwell PM, Coresh J, Hamet P, Tremblay J, Turner ST, de Andrade M, Rao M, Schmidt R, Crick PA, Robino A, Peralta CA, Jukema JW, Mitchell P, Rosas SE, Wang JJ, Scott RJ, Dichgans M, Mitchell BD, Kao WH, Fox CS, Levi C, Attia J, Markus HS, on behalf of the CC, the International Stroke Genetics C. Polygenic Overlap Between Kidney Function and Large Artery Atherosclerotic Stroke. Stroke. 2014;45(12):3508-13. doi: 10.1161/STROKEAHA.114.006609. (PubMed ID Number: 25352485; PMCID: PMC4245455).
Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borinskaya SA, Finan C, Shah S, Kuchenbaecker KB, Shah T, Engmann J, Folkersen L, Eriksson P, Ricceri F, Melander O, Sacerdote C, Gamble DM, Rayaprolu S, Ross OA, McLachlan S, Vikhireva O, Sluijs I, Scott RA, Adamkova V, Flicker L, Bockxmeer FM, Power C, Marques-Vidal P, Meade T, Marmot MG, Ferro JM, Paulos-Pinheiro S, Humphries SE, Talmud PJ, Mateo Leach I, Verweij N, Linneberg A, Skaaby T, Doevendans PA, Cramer MJ, Harst P, Klungel OH, Dowling NF, Dominiczak AF, Kumari M, Nicolaides AN, Weikert C, Boeing H, Ebrahim S, Gaunt TR, Price JF, Lannfelt L, Peasey A, Kubinova R, Pajak A, Malyutina S, Voevoda MI, Tamosiunas A, Maitland-van der Zee AH, Norman PE, Hankey GJ, Bergmann MM, Hofman A, Franco OH, Cooper J, Palmen J, Spiering W, Jong PA, Kuh D, Hardy R, Uitterlinden AG, Ikram MA, Ford I, Hypponen E, Almeida OP, Wareham NJ, Khaw KT, Hamsten A, Husemoen LL, Tjonneland A, Tolstrup JS, Rimm E, Beulens JW, Verschuren WM, Onland-Moret NC, Hofker MH, Wannamethee SG, Whincup PH, Morris R, Vicente AM, Watkins H, Farrall M, Jukema JW, Meschia J, Cupples LA, Sharp SJ, Fornage M, Kooperberg C, LaCroix AZ, Dai JY, Lanktree MB, Siscovick DS, Jorgenson E, Spring B, Coresh J, Li YR, Buxbaum SG, Schreiner PJ, Ellison RC, Tsai MY, Patel SR, Redline S, Johnson AD, Hoogeveen RC, Hakonarson H, Rotter JI, Boerwinkle E, Bakker PI, Kivimaki M, Asselbergs FW, Sattar N, Lawlor DA, Whittaker J, Davey Smith G, Mukamal K, Psaty BM, Wilson JG, Lange LA, Hamidovic A, Hingorani AD, Nordestgaard BG, Bobak M, Leon DA, Langenberg C, Palmer TM, Reiner AP, Keating BJ, Dudbridge F, Casas JP, InterAct C. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ (Clinical research ed). 2014;349:g4164. doi: 10.1136/bmj.g4164. (PubMed ID Number: 25011450; PMCID: PMC4091648).
Hruby A, Meigs JB, O’Donnell CJ, Jacques PF, McKeown NM. Higher magnesium intake reduces risk of impaired glucose and insulin metabolism and progression from prediabetes to diabetes in middle-aged Americans. Diabetes Care. 2014;37(2):419-27. doi: 10.2337/dc13-1397. (PubMed ID Number: 24089547; PMCID: PMC3898748).
Hruby A, O’Donnell CJ, Jacques PF, Meigs JB, Hoffmann U, McKeown NM. Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study. JACC Cardiovascular imaging. 2014;7(1):59-69. doi: 10.1016/j.jcmg.2013.10.006. (PubMed ID Number: 24290571; PMCID: PMC3957229).
Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Tregouet DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Bohm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA, Cohorts for H, Aging Research in Genome Epidemiology Consortium Neurology Working G, Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, Franco-Cereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP, Consortium CA, Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O’Donnell CJ, Group CCHFW. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101. doi: 10.1161/ATVBAHA.113.302088. (PubMed ID Number: 24578379; PMCID: PMC4009733).
Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O’Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, Schmidt H, Lahti J, Heckbert SR, Lumley T, Rice K, Rotter JI, Taylor KD, Folsom AR, Boerwinkle E, Rosamond WD, Shahar E, Gottesman RF, Koudstaal PJ, Amin N, Wieberdink RG, Dehghan A, Hofman A, Uitterlinden AG, Destefano AL, Debette S, Xue L, Beiser A, Wolf PA, Decarli C, Ikram MA, Seshadri S, Mosley TH, Jr., Longstreth WT, Jr., van Duijn CM, Launer LJ. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014;45(2):403-12. doi: 10.1161/STROKEAHA.113.003044. (PubMed ID Number: 24436238; PMCID: PMC3955258).
Irvin MR, Zhi D, Joehanes R, Mendelson M, Aslibekyan S, Claas SA, Thibeault KS, Patel N, Day K, Waite Jones L, Liang L, Chen BH, Yao C, Tiwari HK, Ordovas JM, Levy D, Absher D, Arnett DK. Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid Lowering Drugs and Diet Network Study. Circulation. 2014;130(7):565-72. doi: 10.1161/CIRCULATIONAHA.114.009158. (PubMed ID Number: 24920721; PMCID: PMC4209699).
J. S, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, LifeLines Cohort S, Lluis-Ganella C, Luan J, Lyytikainen LP, Nolte IM, Sim X, Sober S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kahonen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Volker U, Volzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimaki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014;95(1):24-38. doi: 10.1016/j.ajhg.2014.05.010. (PubMed ID Number: 24954895; PMCID: PMC4085636).
Joshi PH, Toth PP, Lirette ST, Griswold ME, Massaro JM, Martin SS, Blaha MJ, Kulkarni KR, Khokhar AA, Correa A, D’Agustino RB, Sr., Jones SR, on behalf of the Lipoprotein Investigators Collaborative Study G. Association of high-density lipoprotein subclasses and incident coronary heart disease: The Jackson Heart and Framingham Offspring Cohort Studies. European journal of preventive cardiology. 2014. doi: 10.1177/2047487314543890. (PubMed ID Number: 25062744; PMCID: PMC4312248).
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014;76(3):379-92. doi: 10.1002/ana.24219. (PubMed ID Number: 25043464).
Kaur B, Himali JJ, Seshadri S, Beiser AS, Au R, McKee AC, Auerbach S, Wolf PA, DeCarli CS. Association between neuropathology and brain volume in the Framingham heart study. Alzheimer Dis Assoc Disord. 2014;28(3):219-25. doi: 10.1097/WAD.0000000000000032. (PubMed ID Number: 24614264; PMCID: PMC4139422).
Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, Qayyum R, Yanek LR, Becker DM, Becker LC, Kooperberg C, Keating B, Reis J, Tang H, Boerwinkle E, Kamatani Y, Matsuda K, Kamatani N, Nakamura Y, Kubo M, Liu S, Dehghan A, Felix JF, Hofman A, Uitterlinden AG, van Duijn CM, Franco OH, Longo DL, Singleton AB, Psaty BM, Evans MK, Cupples LA, Rotter JI, O’Donnell CJ, Takahashi A, Wilson JG, Ganesh SK, Nalls MA, Hematology C, Cogent, BioBank Japan Project Working G. Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014;23(25):6944-60. doi: 10.1093/hmg/ddu401. (PubMed ID Number: 25096241; PMCID: PMC4245044).
Kim EJ, Lyass A, Wang N, Massaro JM, Fox CS, Benjamin EJ, Magnani JW. Relation of hypothyroidism and incident atrial fibrillation (from the Framingham heart study). Am Heart J. 2014;167(1):123-6. doi: 10.1016/j.ahj.2013.10.012. (PubMed ID Number: 24332151; PMCID: PMC3868014).
Kim JH, Song P, Lim H, Lee JH, Lee JH, Park SA. Gene-based rare allele analysis identified a risk gene of Alzheimer’s disease. PloS one. 2014;9(10):e107983. Epub 2014/10/21. doi: 10.1371/journal.pone.0107983. (PubMed ID Number: 25329708; PMCID: PMC4203677).
Konstantinidou V, Ruiz LA, Ordovas JM. Personalized nutrition and cardiovascular disease prevention: From Framingham to PREDIMED. Advances in nutrition. 2014;5(3):368S-71S. doi: 10.3945/an.113.005686. (PubMed ID Number: 24829490; PMCID: PMC4013195).
Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpelainen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, Morris A, Pendergrass SA, Sun YV, Ritchie MD, Vaez A, Lin H, Ligthart S, Marullo L, Rohde R, Shao Y, Ziegler MA, Im HK, Cross Consortia Pleiotropy G, Cohorts for Heart a, Aging Research in Genetic E, Genetic Investigation of Anthropometric Traits C, Global Lipids Genetics C, Meta-Analyses of G, Insulin-related traits C, Global BC, Consortium AD, Women’s Genome Health S, Howard University Family S, Schnabel RB, Jorgensen T, Jorgensen ME, Hansen T, Pedersen O, Stolk RP, Snieder H, Hofman A, Uitterlinden AG, Franco OH, Ikram MA, Richards JB, Rotimi C, Wilson JG, Lange L, Ganesh SK, Nalls M, Rasmussen-Torvik LJ, Pankow JS, Coresh J, Tang W, Linda Kao WH, Boerwinkle E, Morrison AC, Ridker PM, Becker DM, Rotter JI, Kardia SL, Loos RJ, Larson MG, Hsu YH, Province MA, Tracy R, Voight BF, Vaidya D, O’Donnell CJ, Benjamin EJ, Alizadeh BZ, Prokopenko I, Meigs JB, Borecki IB. Pleiotropic genes for metabolic syndrome and inflammation. Molecular genetics and metabolism. 2014;112(4):317-38. doi: 10.1016/j.ymgme.2014.04.007. (PubMed ID Number: 24981077; PMCID: PMC4122618).
Kulminski AM, Arbeev KG, Culminskaya I, Arbeeva L, Ukraintseva SV, Stallard E, Christensen K, Schupf N, Province MA, Yashin AI. Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan. PLoS Genet. 2014;10(1):e1004141. doi: 10.1371/journal.pgen.1004141. (PubMed ID Number: 24497847; PMCID: PMC3907310).
Kwan JS, Hsu YH, Cheung CL, Dupuis J, Saint-Pierre A, Eriksson J, Handelman SK, Aragaki A, Karasik D, Pramstaller PP, Kooperberg C, LaCroix AZ, Larson MG, Lau KS, Lorentzon M, Pichler I, Sham PC, Taliun D, Vandenput L, Kiel DP, Hicks AA, Jackson RD, Ohlsson C, Benjamin EJ, Kung AW. Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Hum Mol Genet. 2014;23(24):6684-93. doi: 10.1093/hmg/ddu386. (PubMed ID Number: 25080503; PMCID: PMC4240210).
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V, Jr., Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Saetrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O’Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ, Project NGOES. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014;94(2):233-45. doi: 10.1016/j.ajhg.2014.01.010. (PubMed ID Number: 24507775; PMCID: PMC3928660).
Lemaitre RN, Johnson CO, Hesselson S, Sotoodehnia N, McKnight B, Sitlani CM, Rea TD, King IB, Kwok PY, Mak A, Li G, Brody J, Larson E, Mozaffarian D, Psaty BM, Huertas-Vazquez A, Tardif JC, Albert CM, Lyytikainen LP, Arking DE, Kaab S, Huikuri HV, Krijthe BP, Eijgelsheim M, Wang YA, Reinier K, Lehtimaki T, Pulit SL, Brugada R, Muller-Nurasyid M, Newton-Cheh CH, Karhunen PJ, Stricker BH, Goyette P, Rotter JI, Chugh SS, Chakravarti A, Jouven X, Siscovick DS. Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. Heart Rhythm. 2014;11(3):471-7. doi: 10.1016/j.hrthm.2014.01.008. (PubMed ID Number: 24418166; PMCID: PMC3966996).
Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Muller-Myhsok B, Jamain S, Leboyer M, Landen M, Thompson PM, Cichon S, Nothen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Arias Vasquez A, Hibar DP, Franke B, Martin NG, Wright MJ, Moo DSBC, Swedish Bipolar Study G, Alzheimer’s Disease Neuroimaging I, Consortium E, Consortium C, Su B. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular psychiatry. 2014;19(4):452-61. doi: 10.1038/mp.2013.37. (PubMed ID Number: 23568192; PMCID: PMC3937299).
Liao SY, Lin X, Christiani DC. Genome-wide Association and Network Analysis of Lung Function in the Framingham Heart Study. Genet Epidemiol. 2014;38(6):572-8. doi: 10.1002/gepi.21841. (PubMed ID Number: 25044411; PMCID: PMC4127157).
Lieb W, Gona P, Larson MG, Aragam J, Zile MR, Cheng S, Benjamin EJ, Vasan RS. The Natural History of Left Ventricular Geometry in the Community: Clinical Correlates and Prognostic Significance of Change in LV Geometric Pattern. JACC Cardiovascular imaging. 2014;7(9):870-8. doi: 10.1016/j.jcmg.2014.05.008. (PubMed ID Number: 25129518; PMCID: PMC4163746).
Lin H, Dolmatova EV, Morley MP, Lunetta KL, McManus DD, Magnani JW, Margulies KB, Hakonarson H, del Monte F, Benjamin EJ, Cappola TP, Ellinor PT. Gene expression and genetic variation in human atria. Heart Rhythm. 2014;11(2):266-71. doi: 10.1016/j.hrthm.2013.10.051. (PubMed ID Number: 24177373; PMCID: PMC3946863).
Lin H, Joehanes R, Pilling LC, Dupuis J, Lunetta KL, Ying SX, Benjamin EJ, Hernandez D, Singleton A, Melzer D, Munson PJ, Levy D, Ferrucci L, Murabito JM. Whole Blood Gene Expression and Interleukin-6 Levels. Genomics. 2014;104(6 Pt B):490-5. doi: 10.1016/j.ygeno.2014.10.003. (PubMed ID Number: 25311648; PMCID: PMC4262595).
Lin H, Sinner MF, Brody JA, Arking DE, Lunetta KL, Rienstra M, Lubitz SA, Magnani JW, Sotoodehnia N, McKnight B, McManus DD, Boerwinkle E, Psaty BM, Rotter JI, Bis JC, Gibbs RA, Muzny D, Kovar CL, Morrison AC, Gupta M, Folsom AR, Kaab S, Heckbert SR, Alonso A, Ellinor PT, Benjamin EJ, Group CAFW. Targeted sequencing in candidate genes for atrial fibrillation: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Heart Rhythm. 2014;11(3):452-7. doi: 10.1016/j.hrthm.2013.11.012. (PubMed ID Number: 24239840; PMCID: PMC3943920).
Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, Bressler J, Liu X, Davis BC, Johnson AD, O’Donnell CJ, Kovar CL, Dinh H, Wu Y, Newsham I, Chen H, Broka A, DeStefano AL, Gupta M, Lunetta KL, Liu CT, White CC, Xing C, Zhou Y, Benjamin EJ, Schnabel RB, Heckbert SR, Psaty BM, Muzny DM, Cupples LA, Morrison AC, Boerwinkle E. Strategies to Design and Analyze Targeted Sequencing Data: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation Cardiovascular genetics. 2014;7(3):335-43. doi: 10.1161/CIRCGENETICS.113.000350. (PubMed ID Number: 24951659; PMCID: PMC4176824).
Lin H, Yin X, Lunetta KL, Dupuis J, McManus DD, Lubitz SA, Magnani JW, Joehanes R, Munson PJ, Larson MG, Levy D, Ellinor PT, Benjamin EJ. Whole blood gene expression and atrial fibrillation: the Framingham Heart Study. PloS one. 2014;9(5):e96794. doi: 10.1371/journal.pone.0096794. (PubMed ID Number: 24805109; PMCID: PMC4013062).
Liu CK, Lyass A, Massaro JM, D’Agostino RB, Sr., Fox CS, Murabito JM. Chronic kidney disease defined by cystatin C predicts mobility disability and changes in gait speed: the Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2014;69(3):301-7. doi: 10.1093/gerona/glt096. (PubMed ID Number: 23913929; PMCID: PMC3976137).
Liu CT, Buchkovich ML, Winkler TW, Heid IM, African Ancestry Anthropometry Genetics C, Consortium G, Borecki IB, Fox CS, Mohlke KL, North KE, Adrienne Cupples L. Multi-ethnic fine-mapping of 14 central adiposity loci. Hum Mol Genet. 2014;23(17):4738-44. doi: 10.1093/hmg/ddu183. (PubMed ID Number: 24760767; PMCID: PMC4119415).
Liu CT, Young KL, Brody JA, Olden M, Wojczynski MK, Heard-Costa N, Li G, Morrison AC, Muzny D, Gibbs RA, Reid JG, Shao Y, Zhou Y, Boerwinkle E, Heiss G, Wagenknecht L, McKnight B, Borecki IB, Fox CS, North KE, Cupples LA. Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation Cardiovascular genetics. 2014;7(3):344-9. doi: 10.1161/CIRCGENETICS.13.000067. (PubMed ID Number: 24951660; PMCID: PMC4135723).
Liu J, Coady S, Carr JJ, Hoffmann U, Taylor HA, Fox CS. Differential associations of abdominal visceral, subcutaneous adipose tissue with cardiometabolic risk factors between African and European Americans. Obesity (Silver Spring). 2014;22(3):811-8. doi: 10.1002/oby.20307. (PubMed ID Number: 23408700; PMCID: PMC4215565).
Liu J, Yuen J, Kang S. Sleep duration, C-reactive protein and risk of incident coronary heart disease – results from the Framingham Offspring Study. Nutrition, metabolism, and cardiovascular diseases: NMCD. 2014;24(6):600-5. doi: 10.1016/j.numecd.2013.12.012. (PubMed ID Number: 24548663).
Ljungman PL, Wilker EH, Rice MB, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Short-term exposure to air pollution and digital vascular function. American journal of epidemiology. 2014;180(5):482-9. doi: 10.1093/aje/kwu161. (PubMed ID Number: 25100647; PMCID: PMC4143083).
London SJ, Gao W, Gharib SA, Hancock DB, Wilk JB, House JS, Gibbs RA, Muzny DM, Lumley T, Franceschini N, North KE, Psaty BM, Kovar CL, Coresh J, Zhou Y, Heckbert SR, Brody JA, Morrison AC, Dupuis J. ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation Cardiovascular genetics. 2014;7(3):350-8. doi: 10.1161/CIRCGENETICS.113.000066. (PubMed ID Number: 24951661; PMCID: PMC4136502).
Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kahonen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Vinuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietilainen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Volzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O’Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Glaser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliovaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melen E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature genetics. 2014;46(7):669-77. doi: 10.1038/ng.3011. (PubMed ID Number: 24929828; PMCID: PMC4140093).
Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dorr M, Ozaki K, Smith AV, Muller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kaab S, Mahida S, Kathiresan S, Kubo M, Launer LJ, Macfarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Volker U, Volzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, Marz W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT. Novel Genetic Markers Associate with Atrial Fibrillation Risk in Europeans and Japanese. J Am Coll Cardiol. 2014;63(12):1200-10. doi: 10.1016/j.jacc.2013.12.015. (PubMed ID Number: 24486271; PMCID: PMC4009240).
Luneburg N, Lieb W, Zeller T, Chen MH, Maas R, Carter AM, Xanthakis V, Glazer NL, Schwedhelm E, Seshadri S, Ikram MA, Longstreth WT, Jr., Fornage M, Konig IR, Loley C, Ojeda FM, Schillert A, Wang TJ, Sticht H, Kittel A, Konig J, Benjamin EJ, Sullivan LM, Bernges I, Anderssohn M, Ziegler A, Gieger C, Illig T, Meisinger C, Wichmann HE, Wild PS, Schunkert H, Psaty BM, Wiggins KL, Heckbert SR, Smith N, Lackner K, Lunetta KL, Blankenberg S, Erdmann J, Munzel T, Grant PJ, Vasan RS, Boger RH. Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine. Circulation Cardiovascular genetics. 2014;7(6):864-72. doi: 10.1161/CIRCGENETICS.113.000264. (PubMed ID Number: 25245031).
Ma J, Sloan M, Fox CS, Hoffmann U, Smith CE, Saltzman E, Rogers GT, Jacques PF, McKeown NM. Sugar-sweetened beverage consumption is associated with abdominal fat partitioning in healthy adults. J Nutr. 2014;144(8):1283-90. doi: 10.3945/jn.113.188599. (PubMed ID Number: 24944282; PMCID: PMC4093984).
Macri V, Mahida SN, Zhang ML, Sinner MF, Dolmatova EV, Tucker NR, McLellan M, Shea MA, Milan DJ, Lunetta KL, Benjamin EJ, Ellinor PT. A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation. Heart Rhythm. 2014;11(6):1055-62. doi: 10.1016/j.hrthm.2014.03.002. (PubMed ID Number: 24607718; PMCID: PMC4130372).
Magnani JW, Benjamin EJ. Where do we come from? Where are we going? Adverse outcomes in catheter ablation for atrial fibrillation. Circ Arrhythm Electrophysiol. 2014;7(2):195-7. doi: 10.1161/CIRCEP.114.001577. (PubMed ID Number: 24736422; PMCID: PMC4058765).
Magnani JW, Brody JA, Prins BP, Arking DE, Lin H, Yin X, Liu CT, Morrison AC, Zhang F, Spector TD, Alonso A, Bis JC, Heckbert SR, Lumley T, Sitlani CM, Cupples LA, Lubitz SA, Soliman EZ, Pulit SL, Newton-Cheh C, O’Donnell CJ, Ellinor PT, Benjamin EJ, Muzny DM, Gibbs RA, Santibanez J, Taylor HA, Rotter JI, Lange LA, Psaty BM, Jackson R, Rich SS, Boerwinkle E, Jamshidi Y, Sotoodehnia N, Consortium C, Project NES, Uk10K. Sequencing of SCN5A Identifies Rare and Common Variants Associated With Cardiac Conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Circulation Cardiovascular genetics. 2014;7(3):365-73. doi: 10.1161/CIRCGENETICS.113.000098. (PubMed ID Number: 24951663; PMCID: PMC4177904).
Magnani JW, Moser CB, Murabito JM, Sullivan LM, Wang N, Ellinor PT, Vasan RS, Benjamin EJ, Coviello AD. Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. Circ Arrhythm Electrophysiol. 2014;7(2):307-12. doi: 10.1161/CIRCEP.113.001322. (PubMed ID Number: 24610804; PMCID: PMC4035016).
Magnani JW, Yin X, McManus DD, Chuang ML, Cheng S, Lubitz SA, Arora G, Manning WJ, Ellinor PT, Benjamin EJ. Genetic Loci associated with atrial fibrillation: relation to left atrial structure in the Framingham Heart Study. Journal of the American Heart Association. 2014;3(2):e000616. doi: 10.1161/JAHA.113.000616. (PubMed ID Number: 24695651; PMCID: PMC4187503).
Mahmood SS, Levy D, Vasan RS, Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet. 2014;383(9921):999-1008. doi: 10.1016/S0140-6736(13)61752-3. (PubMed ID Number: 24084292; PMCID: PMC4159698).
Makarem N, Scott M, Quatromoni P, Jacques P, Parekh N. Trends in dietary carbohydrate consumption from 1991 to 2008 in the Framingham Heart Study Offspring Cohort. Br J Nutr. 2014:1-14. doi: 10.1017/S0007114513004443. (PubMed ID Number: 24661608; PMCID: PMC4175294).
Makinen VP, Civelek M, Meng Q, Zhang B, Zhu J, Levian C, Huan T, Segre AV, Ghosh S, Vivar J, Nikpay M, Stewart AF, Nelson CP, Willenborg C, Erdmann J, Blakenberg S, O’Donnell CJ, Marz W, Laaksonen R, Epstein SE, Kathiresan S, Shah SH, Hazen SL, Reilly MP, Coronary ADG-WR, Meta-Analysis C, Lusis AJ, Samani NJ, Schunkert H, Quertermous T, McPherson R, Yang X, Assimes TL. Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. PLoS Genet. 2014;10(7):e1004502. doi: 10.1371/journal.pgen.1004502. (PubMed ID Number: 25033284; PMCID: PMC4102418).
Malik R, Bevan S, Nalls MA, Holliday EG, Devan WJ, Cheng YC, Ibrahim-Verbaas CA, Verhaaren BF, Bis JC, Joon AY, de Stefano AL, Fornage M, Psaty BM, Ikram MA, Launer LJ, van Duijn CM, Sharma P, Mitchell BD, Rosand J, Meschia JF, Levi C, Rothwell PM, Sudlow C, Markus HS, Seshadri S, Dichgans M, Wellcome Trust Case Control C. Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke. 2014;45(2):394-402. doi: 10.1161/STROKEAHA.113.002938. (PubMed ID Number: 24436234; PMCID: PMC4006951).
Marino M, Li Y, Pencina MJ, D’Agostino RB, Sr., Berkman LF, Buxton OM. Quantifying cardiometabolic risk using modifiable non-self-reported risk factors. Am J Prev Med. 2014;47(2):131-40. doi: 10.1016/j.amepre.2014.03.006. (PubMed ID Number: 24951039; PMCID: PMC4107093).
Martini S, Nair V, Keller BJ, Eichinger F, Hawkins JJ, Randolph A, Boger CA, Gadegbeku CA, Fox CS, Cohen CD, Kretzler M, European Renal c DNAB, Cohort CP, Consortium CK. Integrative Biology Identifies Shared Transcriptional Networks in CKD. J Am Soc Nephrol. 2014;25(11):2559-72. doi: 10.1681/ASN.2013080906. (PubMed ID Number: 24925724; PMCID: PMC4214523).
McMahon GM, Olden M, Garnaas M, Yang Q, Liu X, Hwang SJ, Larson MG, Consortium CK, Goessling W, Fox CS. Sequencing of LRP2 Reveals Multiple Rare Variants Associated with Urinary Trefoil Factor-3. J Am Soc Nephrol. 2014;25(12):2896-905. doi: 10.1681/ASN.2013111240. (PubMed ID Number: 24876117; PMCID: PMC4243354).
McMahon GM, O’Seaghdha CM, Hwang SJ, Meigs JB, Fox CS. The association of a single-nucleotide polymorphism in CUBN and the risk of albuminuria and cardiovascular disease. Nephrol Dial Transplant. 2014;29(2):342-7. doi: 10.1093/ndt/gft386. (PubMed ID Number: 24052458; PMCID: PMC3968306).
McMahon GM, Preis SR, Hwang SJ, Fox CS. Mid-Adulthood Risk Factor Profiles for CKD. J Am Soc Nephrol. 2014;25(11):2633-41. doi: 10.1681/ASN.2013070750. (PubMed ID Number: 24970884; PMCID: PMC4214518).
McManus DD, Lin H, Tanriverdi K, Quercio M, Yin X, Larson MG, Ellinor PT, Levy D, Freedman JE, Benjamin EJ. Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study. Heart Rhythm. 2014;11(4):663-9. doi: 10.1016/j.hrthm.2014.01.018. (PubMed ID Number: 24444445; PMCID: PMC4219255).
Moore LL, Chadid S, Singer MR, Kreger BE, Denis GV. Metabolic Health Reduces Risk of Obesity-Related Cancer in Framingham Study Adults. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014;23(10):2057-65. doi: 10.1158/1055-9965.EPI-14-0240. (PubMed ID Number: 25012997; PMCID: PMC4184957).
Morrison AC, Bis JC, Hwang SJ, Ehret GB, Lumley T, Rice K, Muzny D, Gibbs RA, Boerwinkle E, Psaty BM, Chakravarti A, Levy D. Sequence Analysis of Six Blood Pressure Candidate Regions in 4,178 Individuals: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. PloS one. 2014;9(10):e109155. doi: 10.1371/journal.pone.0109155. (PubMed ID Number: 25275628; PMCID: PMC4183565).
Murabito JM, Beiser AS, Decarli C, Seshadri S, Wolf PA, Au R. Parental longevity is associated with cognition and brain ageing in middle-aged offspring. Age and ageing. 2014;43(3):358-63. doi: 10.1093/ageing/aft175. (PubMed ID Number: 24212919; PMCID: PMC4001170).
Myocardial Infarction Genetics Consortium I, Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, Konig I, Asselta R, Merlini PA, Marziliano N, Notarangelo MF, Schick U, Auer P, Assimes TL, Reilly M, Wilensky R, Rader DJ, Hovingh GK, Meitinger T, Kessler T, Kastrati A, Laugwitz KL, Siscovick D, Rotter JI, Hazen SL, Tracy R, Cresci S, Spertus J, Jackson R, Schwartz SM, Natarajan P, Crosby J, Muzny D, Ballantyne C, Rich SS, O’Donnell CJ, Abecasis G, Sunyaev S, Nickerson DA, Buring JE, Ridker PM, Chasman DI, Austin E, Ye Z, Kullo IJ, Weeke PE, Shaffer CM, Bastarache LA, Denny JC, Roden DM, Palmer C, Deloukas P, Lin DY, Tang ZZ, Erdmann J, Schunkert H, Danesh J, Marrugat J, Elosua R, Ardissino D, McPherson R, Watkins H, Reiner AP, Wilson JG, Altshuler D, Gibbs RA, Lander ES, Boerwinkle E, Gabriel S, Kathiresan S. Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med. 2014;371(22):2072-82. doi: 10.1056/NEJMoa1405386. (PubMed ID Number: 25390462; PMCID: PMC4335708).
Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R, International Parkinson’s Disease Genomics C, Parkinson’s Study Group Parkinson’s Research: The Organized GI, andMe, GenePd, NeuroGenetics Research C, Hussman Institute of Human G, Ashkenazi Jewish Dataset I, Cohorts for H, Aging Research in Genetic E, North American Brain Expression C, United Kingdom Brain Expression C, Greek Parkinson’s Disease C, Alzheimer Genetic Analysis G, Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease. Nature genetics. 2014;46(9):989-93. doi: 10.1038/ng.3043. (PubMed ID Number: 25064009; PMCID: PMC4146673).
Neogi T, Soni A, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, Zhang W, Muir KR, Wheeler M, Cooper C, Spector TD, Cicuttini F, Jones G, Nevitt M, Liu Y, Arden NK, Doherty M, Valdes AM. Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis. Ann Rheum Dis. 2014;73(1):315-7. doi: 10.1136/annrheumdis-2013-203836. (PubMed ID Number: 23852765; PMCID: PMC3908666).
Nishtala A, Preis SR, Beiser A, Devine S, Hankee L, Seshadri S, Wolf PA, Au R. Midlife cardiovascular risk impacts executive function: Framingham offspring study. Alzheimer Dis Assoc Disord. 2014;28(1):16-22. doi: 10.1097/WAD.0b013e3182a715bc. (PubMed ID Number: 23995818; PMCID: PMC3945114).
Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gomez C, Vandenput L, Kim GS, Hun Lee S, Castano-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellstrom D, Herrera L, Karlsson MK, Hofman A, Ljunggren O, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone. 2014;59:20-7. (PubMed ID Number: 24516880; PMCID: PMC4102322).
Olden M, Corre T, Hayward C, Toniolo D, Ulivi S, Gasparini P, Pistis G, Hwang SJ, Bergmann S, Campbell H, Cocca M, Gandin I, Girotto G, Glaudemans B, Hastie ND, Loffing J, Polasek O, Rampoldi L, Rudan I, Sala C, Traglia M, Vollenweider P, Vuckovic D, Youhanna S, Weber J, Wright AF, Kutalik Z, Bochud M, Fox CS, Devuyst O. Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis. J Am Soc Nephrol. 2014;25(8):1869-82. doi: 10.1681/ASN.2013070781. (PubMed ID Number: 24578125; PMCID: PMC4116060).
O’Malley AJ, Elwert F, Rosenquist JN, Zaslavsky AM, Christakis NA. Estimating peer effects in longitudinal dyadic data using instrumental variables. Biometrics. 2014. doi: 10.1111/biom.12172. (PubMed ID Number: 24779654; PMCID: PMC4213357).
O’Neal WT, Efird JT, Dawood FZ, Yeboah J, Alonso A, Heckbert SR, Soliman EZ. Coronary Artery Calcium and Risk of Atrial Fibrillation (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol. 2014;114(11):1707-12. doi: 10.1016/j.amjcard.2014.09.005. (PubMed ID Number: 25282316; PMCID: PMC4253067).
O’Seaghdha CM, Tin A, Yang Q, Katz R, Liu Y, Harris T, Astor B, Coresh J, Fox CS, Kao WH, Shlipak MG. Association of a Cystatin C Gene Variant With Cystatin C Levels, CKD, and Risk of Incident Cardiovascular Disease and Mortality. Am J Kidney Dis. 2014;63(1):16-22. doi: 10.1053/j.ajkd.2013.06.015. (PubMed ID Number: 23932088; PMCID: PMC3872167).
Pei YF, Zhang L, Liu Y, Li J, Shen H, Liu YZ, Tian Q, He H, Wu S, Ran S, Han Y, Hai R, Lin Y, Zhu J, Zhu XZ, Papasian CJ, Deng HW. Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity. Hum Mol Genet. 2014;23(3):820-30. doi: 10.1093/hmg/ddt464. (PubMed ID Number: 24064335; PMCID: PMC3888264).
Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, Manichaikul A, Davis B, Lohman K, Joon AY, Smith AV, Grove ML, Zanoni P, Redon V, Demissie S, Lawson K, Peters U, Carlson C, Jackson RD, Ryckman KK, Mackey RH, Robinson JG, Siscovick DS, Schreiner PJ, Mychaleckyj JC, Pankow JS, Hofman A, Uitterlinden AG, Harris TB, Taylor KD, Stafford JM, Reynolds LM, Marioni RE, Dehghan A, Franco OH, Patel AP, Lu Y, Hindy G, Gottesman O, Bottinger EP, Melander O, Orho-Melander M, Loos RJ, Duga S, Merlini PA, Farrall M, Goel A, Asselta R, Girelli D, Martinelli N, Shah SH, Kraus WE, Li M, Rader DJ, Reilly MP, McPherson R, Watkins H, Ardissino D, Project NGES, Zhang Q, Wang J, Tsai MY, Taylor HA, Correa A, Griswold ME, Lange LA, Starr JM, Rudan I, Eiriksdottir G, Launer LJ, Ordovas JM, Levy D, Chen YD, Reiner AP, Hayward C, Polasek O, Deary IJ, Borecki IB, Liu Y, Gudnason V, Wilson JG, van Duijn CM, Kooperberg C, Rich SS, Psaty BM, Rotter JI, O’Donnell CJ, Rice K, Boerwinkle E, Kathiresan S, Cupples LA. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014;94(2):223-32. doi: 10.1016/j.ajhg.2014.01.009. (PubMed ID Number: 24507774; PMCID: PMC3928662).
Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tsernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Hua Zhao J, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collee JM, Couch FJ, Couper D, Coviello AD, Cox A, Czene K, D’Adamo A P, Davey Smith G, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, Garcia-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guenel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, Magi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylkas K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, Stockl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, Volzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, Australian Ovarian Cancer S, Network G, kConFab, LifeLines Cohort S, InterAct C, Early Growth Genetics C, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, Jarvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, Sorensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014;514(7520):92-7. doi: 10.1038/nature13545. (PubMed ID Number: 25231870; PMCID: PMC4185210).
Piccini JP, Hammill BG, Sinner MF, Hernandez AF, Walkey AJ, Benjamin EJ, Curtis LH, Heckbert SR. Clinical course of atrial fibrillation in older adults: the importance of cardiovascular events beyond stroke. Eur Heart J. 2014;35(4):250-6. doi: 10.1093/eurheartj/eht483. (PubMed ID Number: 24282186; PMCID: PMC3896863).
Pottala JV, Djira GD, Espeland MA, Ye J, Larson MG, Harris WS. Structural equation modeling for analyzing erythrocyte fatty acids in Framingham. Computational and mathematical methods in medicine. 2014;2014:160520. doi: 10.1155/2014/160520. (PubMed ID Number: 24959197; PMCID: PMC4052884).
Qi Q, Kilpelainen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renstrom F, Lin X, Angquist LH, Huang J, Liu Z, Li Y, Asif Ali M, Xu M, Ahluwalia TS, Boer JM, Chen P, Daimon M, Eriksson J, Perola M, Friedlander Y, Gao YT, Heppe DH, Holloway JW, Houston DK, Kanoni S, Kim YM, Laaksonen MA, Jaaskelainen T, Lee NR, Lehtimaki T, Lemaitre RN, Lu W, Luben RN, Manichaikul A, Mannisto S, Marques-Vidal P, Monda KL, Ngwa JS, Perusse L, van Rooij FJ, Xiang YB, Wen W, Wojczynski MK, Zhu J, Borecki IB, Bouchard C, Cai Q, Cooper C, Dedoussis GV, Deloukas P, Ferrucci L, Forouhi NG, Hansen T, Christiansen L, Hofman A, Johansson I, Jorgensen T, Karasawa S, Khaw KT, Kim MK, Kristiansson K, Li H, Lin X, Liu Y, Lohman KK, Long J, Mikkila V, Mozaffarian D, North K, Pedersen O, Raitakari O, Rissanen H, Tuomilehto J, van der Schouw YT, Uitterlinden AG, Zillikens MC, Franco OH, Shyong Tai E, Ou Shu X, Siscovick DS, Toft U, Verschuren WM, Vollenweider P, Wareham NJ, Witteman JC, Zheng W, Ridker PM, Kang JH, Liang L, Jensen MK, Curhan GC, Pasquale LR, Hunter DJ, Mohlke KL, Uusitupa M, Cupples LA, Rankinen T, Orho-Melander M, Wang T, Chasman DI, Franks PW, Sorensen TI, Hu FB, Loos RJ, Nettleton JA, Qi L. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet. 2014;23(25):6961-72. Epub 2014/08/12. doi: 10.1093/hmg/ddu411. (PubMed ID Number: 25104851; PMCID: PMC4271061).
Rahman F, Kwan GF, Benjamin EJ. Global epidemiology of atrial fibrillation. Nat Rev Cardiol. 2014;11(11):639-54. doi: 10.1038/nrcardio.2014.118. (PubMed ID Number: 25113750).
Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, Kornhuber J, Peters O, Naj AC, Chouraki V, Bellenguez C, Gerrish A, Heun R, Frolich L, Hull M, Buscemi L, Herms S, Kolsch H, Scheltens P, Breteler MM, Ruther E, Wiltfang J, Goate A, Jessen F, Maier W, Heneka MT, Becker T, Nothen MM. SUCLG2 identified as both a determinator of CSF Abeta1-42 levels and an attenuator of cognitive decline in Alzheimer’s disease. Hum Mol Genet. 2014;23(24):6644-58. Epub 2014/07/17. doi: 10.1093/hmg/ddu372. (PubMed ID Number: 25027320; PMCID: PMC4240204).
Ramos YF, Metrustry S, Arden N, Bay-Jensen AC, Beekman M, de Craen AJ, Cupples LA, Esko T, Evangelou E, Felson DT, Hart DJ, Ioannidis JP, Karsdal M, Kloppenburg M, Lafeber F, Metspalu A, Panoutsopoulou K, Slagboom PE, Spector TD, van Spil EW, Uitterlinden AG, Zhu Y, arc Oc, Treat OAc, Valdes AM, van Meurs JB, Meulenbelt I, arc Oc. Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. J Med Genet. 2014;51(9):596-604. doi: 10.1136/jmedgenet-2014-102478. (PubMed ID Number: 25057126).
Rasheed H, Hughes K, Flynn TJ, Merriman TR. Mendelian Randomization Provides No Evidence for a Causal Role of Serum Urate in Increasing Serum Triglyceride Levels. Circulation Cardiovascular genetics. 2014;7(6):830-7. doi: 10.1161/CIRCGENETICS.114.000556. (PubMed ID Number: 25249548; PMCID: PMC4270849).
Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Jr., Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014;167(1):109-15 e2. doi: 10.1016/j.ahj.2013.10.003. (PubMed ID Number: 24332149; PMCID: PMC3884900).
Robbins JM, Petrone AB, Ellison RC, Hunt SC, Carr JJ, Heiss G, Arnett DK, Gaziano JM, Djousse L.Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: the NHLBI Family Heart Study. e-SPEN journal. 2014;9(3):e131-e5. doi: 10.1016/j.clnme.2014.04.004. (PubMed ID Number: 25642410; PMCID: PMC4309282).
Roberts LD, Bostrom P, O’Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. beta-Aminoisobutyric acid induces browning of white fat and hepatic beta-oxidation and is inversely correlated with cardiometabolic risk factors. Cell metabolism. 2014;19(1):96-108. doi: 10.1016/j.cmet.2013.12.003. (PubMed ID Number: 24411942; PMCID: PMC4017355).
Romero JR, Preis SR, Beiser A, DeCarli C, Viswanathan A, Martinez-Ramirez S, Kase CS, Wolf PA, Seshadri S. Risk factors, stroke prevention treatments, and prevalence of cerebral microbleeds in the Framingham Heart Study. Stroke. 2014;45(5):1492-4. doi: 10.1161/STROKEAHA.114.004130. (PubMed ID Number: 24713533; PMCID: PMC4048617).
Roseman DA, Hwang SJ, Manders ES, O’Donnell CJ, Upadhyay A, Hoffmann U, Fox CS. Renal artery calcium, cardiovascular risk factors, and indexes of renal function. Am J Cardiol. 2014;113(1):156-61. doi: 10.1016/j.amjcard.2013.09.036. (PubMed ID Number: 24210678; PMCID: PMC3882167).
Rosenquist KJ, Therkelsen KE, Massaro JM, Hoffmann U, Fox CS. Development and reproducibility of a computed tomography-based measurement for upper body subcutaneous neck fat. Journal of the American Heart Association. 2014;3(6):e000979. doi: 10.1161/JAHA.114.000979. (PubMed ID Number: 25523152; PMCID: PMC4338686).
Rutter MK, Sullivan LM, Fox CS, Wilson PW, Nathan DM, Vasan RS, D’Agostino RB, Sr., Meigs JB. Baseline Levels, and Changes Over Time in Body Mass Index and Fasting Insulin, and Their Relationship to Change in Metabolic Trait Clustering. Metabolic syndrome and related disorders. 2014;12(7):372-80. doi: 10.1089/met.2013.0148. (PubMed ID Number: 25007010; PMCID: PMC4209491).
Sahni S, Broe KE, Tucker KL, McLean RR, Kiel DP, Cupples LA, Hannan MT. Association of total protein intake with bone mineral density and bone loss in men and women from the Framingham Offspring Study. Public health nutrition. 2014;17(11):2570-6. doi: 10.1017/S1368980013002875. (PubMed ID Number: 24168918; PMCID: PMC4103961).
Scharpf RB, Mireles L, Yang Q, Kottgen A, Ruczinski I, Susztak K, Halper-Stromberg E, Tin A, Cristiano S, Chakravarti A, Boerwinkle E, Fox CS, Coresh J, Linda Kao WH. Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations. BMC Genet. 2014;15:81. doi: 10.1186/1471-2156-15-81. (PubMed ID Number: 25007794; PMCID: PMC4118309).
Sen SK, Boelte KC, Barb JJ, Joehanes R, Zhao X, Cheng Q, Adams L, Teer JK, Accame DS, Chowdhury S, Singh LN, Program NCS, Consortium C, Kavousi M, Peyser PA, Quigley L, Priel DL, Lau K, Kuhns DB, Yoshimura T, Johnson AD, Hwang SJ, Chen MY, Arai AE, Green ED, Mullikin JC, Kolodgie FD, O’Donnell CJ, Virmani R, Munson PJ, McVicar DW, Biesecker LG. Integrative DNA, RNA, and Protein Evidence Connects TREML4 to Coronary Artery Calcification. Am J Hum Genet. 2014;95(1):66-76. doi: 10.1016/j.ajhg.2014.06.003. (PubMed ID Number: 24975946; PMCID: PMC4085627).
Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, LifeLines Cohort S, Lluis-Ganella C, Luan J, Lyytikainen LP, Nolte IM, Sim X, Sober S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kahonen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Volker U, Volzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimaki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014;95(1):24-38. doi: 10.1016/j.ajhg.2014.05.010. (PubMed ID Number: 24954895; PMCID: PMC4085636).
Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kaab S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2014;16(10):1426-33. doi: 10.1093/europace/euu175. (PubMed ID Number: 25037055; PMCID: PMC4197895).
Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Muller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, MacFarlane P, Harris TB, Darbar D, Dorr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden A, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, Consortium M, Consortium AF, Benjamin EJ, Milan DJ, Melander O, Heckbert S, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kaab S, Ellinor PT. Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation. Circulation. 2014;130(15):1225-35. doi: 10.1161/CIRCULATIONAHA.114.009892. (PubMed ID Number: 25124494; PMCID: PMC4190011).
Smith JG, Luk K, Schulz CA, Engert JC, Do R, Hindy G, Rukh G, Dufresne L, Almgren P, Owens DS, Harris TB, Peloso GM, Kerr KF, Wong Q, Smith AV, Budoff MJ, Rotter JI, Cupples LA, Rich S, Kathiresan S, Orho-Melander M, Gudnason V, O’Donnell CJ, Post WS, Thanassoulis G, Cohorts for H, Aging Research in Genetic Epidemiology Extracoronary Calcium Working G. Association of Low-Density Lipoprotein Cholesterol-Related Genetic Variants With Aortic Valve Calcium and Incident Aortic Stenosis. JAMA. 2014;312(17):1764-71. doi: 10.1001/jama.2014.13959. (PubMed ID Number: 25344734; PMCID: PMC4280258).
Sponholtz TR, Zhang X, Fontes JD, Meigs JB, Cupples LA, Kiel DP, Hannan MT, McLean RR. Association between inflammatory biomarkers and bone mineral density in a community-based cohort of men and women. Arthritis Care Res (Hoboken). 2014;66(8):1233-40. doi: 10.1002/acr.22270. (PubMed ID Number: 24375982; PMCID: PMC4069198).
Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM, Kiel DP, Kritchevsky SB, Shardell MD, Dam TT, Vassileva MT. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci. 2014;69(5):547-58. doi: 10.1093/gerona/glu010. (PubMed ID Number: 24737557; PMCID: PMC3991146).
Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol. 2014;34(9):2100-5. doi: 10.1161/ATVBAHA.114.303579. (PubMed ID Number: 25060794; PMCID: PMC4142677).
Sung YJ, Simino J, Kume R, Basson J, Schwander K, Rao DC. Comparison of two methods for analysis of gene-environment interactions in longitudinal family data: the Framingham heart study. Frontiers in genetics. 2014;5:9. doi: 10.3389/fgene.2014.00009. (PubMed ID Number: 24523728; PMCID: PMC3906599).
Tan LJ, Zhu H, He H, Wu KH, Li J, Chen XD, Zhang JG, Shen H, Tian Q, Krousel-Wood M, Papasian CJ, Bouchard C, Perusse L, Deng HW. Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries. PloS one. 2014;9(5):e96149. doi: 10.1371/journal.pone.0096149. (PubMed ID Number: 24879436; PMCID: PMC4039436).
Tang W, Kowgier M, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, Hansen JG, Albrecht E, Aldrich MC, Allerhand M, Barr RG, Brusselle GG, Couper DJ, Curjuric I, Davies G, Deary IJ, Dupuis J, Fall T, Foy M, Franceschini N, Gao W, Glaser S, Gu X, Hancock DB, Heinrich J, Hofman A, Imboden M, Ingelsson E, James A, Karrasch S, Koch B, Kritchevsky SB, Kumar A, Lahousse L, Li G, Lind L, Lindgren C, Liu Y, Lohman K, Lumley T, McArdle WL, Meibohm B, Morris AP, Morrison AC, Musk B, North KE, Palmer LJ, Probst-Hensch NM, Psaty BM, Rivadeneira F, Rotter JI, Schulz H, Smith LJ, Sood A, Starr JM, Strachan DP, Teumer A, Uitterlinden AG, Volzke H, Voorman A, Wain LV, Wells MT, Wilk JB, Williams OD, Heckbert SR, Stricker BH, London SJ, Fornage M, Tobin MD, O’Connor GT, Hall IP, Cassano PA. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. PloS one. 2014;9(7):e100776. doi: 10.1371/journal.pone.0100776. (PubMed ID Number: 24983941; PMCID: PMC4077649).
Torjesen AA, Wang N, Larson MG, Hamburg NM, Vita JA, Levy D, Benjamin EJ, Vasan RS, Mitchell GF. Forward and Backward Wave Morphology and Central Pressure Augmentation in Men and Women in the Framingham Heart Study. Hypertension. 2014;64(2):259-65. doi: 10.1161/HYPERTENSIONAHA.114.03371. (PubMed ID Number: 24866142; PMCID: PMC4184952).
Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O’Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, P MR, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, Marz W, Murray SS, O’Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet. 2014;94(3):349-60. doi: 10.1016/j.ajhg.2013.12.016. (PubMed ID Number: 24560520; PMCID: PMC3951943).
Travison TG, Zhuang WV, Lunetta KL, Karasik D, Bhasin S, Kiel DP, Coviello AD, Murabito JM. The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study. Clinical endocrinology. 2014;80(2):277-82. doi: 10.1111/cen.12260. (PubMed ID Number: 23746309; PMCID: PMC3825765).
Tsao CW, Pencina KM, Massaro JM, Benjamin EJ, Levy D, Vasan RS, Hoffmann U, O’Donnell CJ, Mitchell GF. Cross-Sectional Relations of Arterial Stiffness, Pressure Pulsatility, Wave Reflection, and Arterial Calcification. Arterioscler Thromb Vasc Biol. 2014;34(11):2495-500. doi: 10.1161/ATVBAHA.114.303916. (PubMed ID Number: 25169933; PMCID: PMC4199901).
Vadiveloo M, Scott M, Quatromoni P, Jacques P, Parekh N. Trends in dietary fat and high-fat food intakes from 1991 to 2008 in the Framingham Heart Study participants. Br J Nutr. 2014;111(4):724-34. doi: 10.1017/S0007114513002924. (PubMed ID Number: 24047827; PMCID: PMC4103899).
van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA, Hofman A, Rivadeneira F, Uitterlinden AG, Boerwinkle E, Ballantyne CM, Gudnason V, Psaty BM, Cupples LA, Jarvelin MR, Ripatti S, Isaacs A, Muller-Myhsok B, Karssen LC, van Duijn CM. The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels. PloS one. 2014;9(10):e109290. doi: 10.1371/journal.pone.0109290. (PubMed ID Number: 25329471; PMCID: PMC4203717).
van Schalkwijk DB, de Graaf AA, Tsivtsivadze E, Parnell LD, van der Werff-van der Vat BJ, van Ommen B, van der Greef J, Ordovas JM. Lipoprotein metabolism indicators improve cardiovascular risk prediction. PloS one. 2014;9(3):e92840. doi: 10.1371/journal.pone.0092840. (PubMed ID Number: 24667559; PMCID: PMC3965475).
Velagaleti RS, Gona P, Pencina MJ, Aragam J, Wang TJ, Levy D, D’Agostino RB, Lee DS, Kannel WB, Benjamin EJ, Vasan RS. Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction. Am J Cardiol. 2014;113(1):117-22. doi: 10.1016/j.amjcard.2013.09.028. (PubMed ID Number: 24210333; PMCID: PMC3881171).
Vimaleswaran KS, Cavadino A, Berry DJ, LifeLines Cohort Study i, Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, Houston DK, Ahluwalia TS, van der Most PJ, Pasko D, Zgaga L, Thiering E, Vitart V, Fraser RM, Huffman JE, de Boer RA, Schottker B, Saum KU, McCarthy MI, Dupuis J, Herzig KH, Sebert S, Pouta A, Laitinen J, Kleber ME, Navis G, Lorentzon M, Jameson K, Arden N, Cooper JA, Acharya J, Hardy R, Raitakari O, Ripatti S, Billings LK, Lahti J, Osmond C, Penninx BW, Rejnmark L, Lohman KK, Paternoster L, Stolk RP, Hernandez DG, Byberg L, Hagstrom E, Melhus H, Ingelsson E, Mellstrom D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Tiesler CM, Jula A, Navarro P, Wright AF, Polasek O, International Consortium for Blood P, Cohorts for H, Aging Research in Genomic Epidemiology c, Global Blood Pressure Genetics c, Caroline H, Wilson JF, Rudan I, Salomaa V, Heinrich J, Campbell H, Price JF, Karlsson M, Lind L, Michaelsson K, Bandinelli S, Frayling TM, Hartman CA, Sorensen TI, Kritchevsky SB, Langdahl BL, Eriksson JG, Florez JC, Spector TD, Lehtimaki T, Kuh D, Humphries SE, Cooper C, Ohlsson C, Marz W, de Borst MH, Kumari M, Kivimaki M, Wang TJ, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Hingorani AD, Pilz S, Whittaker JC, Jarvelin MR, Hypponen E. Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The lancet Diabetes & endocrinology. 2014;2(9):719-29. doi: 10.1016/S2213-8587(14)70113-5. (PubMed ID Number: 24974252).
Walford GA, Porneala BC, Dauriz M, Vassy JL, Cheng S, Rhee EP, Wang TJ, Meigs JB, Gerszten RE, Florez JC. Metabolite traits and genetic risk provide complementary information for the prediction of future type 2 diabetes. Diabetes Care. 2014;37(9):2508-14. doi: 10.2337/dc14-0560. (PubMed ID Number: 24947790; PMCID: PMC4140156).
Wang H, Troy LM, Rogers GT, Fox CS, McKeown NM, Meigs JB, Jacques PF. Longitudinal association between dairy consumption and changes of body weight and waist circumference: the Framingham Heart Study. Int J Obes (Lond). 2014;38(2):299-305. doi: 10.1038/ijo.2013.78. (PubMed ID Number: 23736371; PMCID: PMC3809320).
Wang T, Zhou B, Guo T, Bidlingmaier M, Wallaschofski H, Teumer A, Vasan RS, Kaplan RC. A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations. Genet Epidemiol. 2014;38(2):162-71. doi: 10.1002/gepi.21766. (PubMed ID Number: 24446417; PMCID: PMC4049273).
Waterworth DM, Li L, Scott R, Warren L, Gillson C, Aponte J, Sarov-Blat L, Sprecher D, Dupuis J, Reiner A, Psaty BM, Tracy RP, Lin H, McPherson R, Chissoe S, Wareham N, Ehm MG. A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker. Journal of the American Heart Association. 2014;3(4). doi: 10.1161/JAHA.114.001074. (PubMed ID Number: 25164947; PMCID: PMC4310399).
Wei WH, Guo Y, Kindt AS, Merriman TR, Semple CA, Wang K, Haley CS. Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid. Hum Mol Genet. 2014;23(19):5061-8. doi: 10.1093/hmg/ddu227. (PubMed ID Number: 24821702; PMCID: PMC4159153).
Weinberg I, Gona P, O’Donnell CJ, Jaff MR, Murabito JM. The systolic blood pressure difference between arms and cardiovascular disease in the Framingham heart study. Am J Med. 2014;127(3):209-15. doi: 10.1016/j.amjmed.2013.10.027. (PubMed ID Number: 24287007; PMCID: PMC4066378).
Weinstein G, Beiser AS, Choi SH, Preis SR, Chen TC, Vorgas D, Au R, Pikula A, Wolf PA, DeStefano AL, Vasan RS, Seshadri S. Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study. JAMA neurology. 2014;71(1):55-61. doi: 10.1001/jamaneurol.2013.4781. (PubMed ID Number: 24276217; PMCID: PMC4056186).
Weinstein G, Preis SR, Beiser AS, Au R, Kelly-Hayes M, Kase CS, Wolf PA, Seshadri S. Cognitive performance after stroke – The Framingham Heart Study. International journal of stroke: official journal of the International Stroke Society. 2014;9 Suppl A100:48-54. doi: 10.1111/ijs.12275. (PubMed ID Number: 25352473; PMCID: PMC4215163).
Wen CP, Matsushita K, Coresh J, Iseki K, Islam M, Katz R, McClellan W, Peralta CA, Wang H, de Zeeuw D, Astor BC, Gansevoort RT, Levey AS, Levin A. Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar. Kidney Int. 2014;86(4):819-27. Epub 2014/02/14. doi: 10.1038/ki.2013.553. (PubMed ID Number: 24522492; PMCID: PMC4048178).
Weng LC, Tang W, Rich SS, Smith NL, Redline S, O’Donnell CJ, Basu S, Reiner AP, Delaney JA, Tracy RP, Palmer CD, Young T, Yang Q, Folsom AR, Cushman M. A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups. Thromb Res. 2014;134(2):462-7. doi: 10.1016/j.thromres.2014.05.018. (PubMed ID Number: 24908450; PMCID: PMC4111961).
Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, Roubenoff R, Pikula A, Au R, Braverman LE, Wolf PA, Vasan RS, Seshadri S. Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy. Neurology. 2014;82(18):1613-9. doi: 10.1212/WNL.0000000000000382. (PubMed ID Number: 24706014; PMCID: PMC4013812).
Wilker EH, Ljungman PL, Rice MB, Kloog I, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Hamburg NM, Mittleman MA. Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. Am J Cardiol. 2014;113(12):2057-63. doi: 10.1016/j.amjcard.2014.03.048. (PubMed ID Number: 24793676; PMCID: PMC4066389).
Williams SR, Yang Q, Chen F, Liu X, Keene KL, Jacques P, Chen WM, Weinstein G, Hsu FC, Beiser A, Wang L, Bookman E, Doheny KF, Wolf PA, Zilka M, Selhub J, Nelson S, Gogarten SM, Worrall BB, Seshadri S, Sale MM, Genomics, Randomized Trials N, Framingham Heart S. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. PLoS Genet. 2014;10(3):e1004214. doi: 10.1371/journal.pgen.1004214. (PubMed ID Number: 24651765; PMCID: PMC3961178).
Wolf PA. Awareness of the role of atrial fibrillation as a cause of ischemic stroke. Stroke. 2014;45(2):e19-21. doi: 10.1161/STROKEAHA.113.003282. (PubMed ID Number: 24357657; PMCID: PMC3946842).
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Magi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancakova A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlov J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Bluher M, Bolton JL, Bottcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspersen IH, Chines PS, Clarke R, Claudi-Boehm S, Cooper M, Daw EW, De Jong PA, Deelen J, Delgado G, Denny JC, Dhonukshe-Rutten R, Dimitriou M, Doney AS, Dorr M, Eklund N, Eury E, Folkersen L, Garcia ME, Geller F, Giedraitis V, Go AS, Grallert H, Grammer TB, Grassler J, Gronberg H, de Groot LC, Groves CJ, Haessler J, Hall P, Haller T, Hallmans G, Hannemann A, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hemani G, Henders AK, Hillege HL, Hlatky MA, Hoffmann W, Hoffmann P, Holmen O, Houwing-Duistermaat JJ, Illig T, Isaacs A, James AL, Jeff J, Johansen B, Johansson A, Jolley J, Juliusdottir T, Junttila J, Kho AN, Kinnunen L, Klopp N, Kocher T, Kratzer W, Lichtner P, Lind L, Lindstrom J, Lobbens S, Lorentzon M, Lu Y, Lyssenko V, Magnusson PK, Mahajan A, Maillard M, McArdle WL, McKenzie CA, McLachlan S, McLaren PJ, Menni C, Merger S, Milani L, Moayyeri A, Monda KL, Morken MA, Muller G, Muller-Nurasyid M, Musk AW, Narisu N, Nauck M, Nolte IM, Nothen MM, Oozageer L, Pilz S, Rayner NW, Renstrom F, Robertson NR, Rose LM, Roussel R, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Schunkert H, Scott RA, Sehmi J, Seufferlein T, Shi J, Silventoinen K, Smit JH, Smith AV, Smolonska J, Stanton AV, Stirrups K, Stott DJ, Stringham HM, Sundstrom J, Swertz MA, Syvanen AC, Tayo BO, Thorleifsson G, Tyrer JP, van Dijk S, van Schoor NM, van der Velde N, van Heemst D, van Oort FV, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Waldenberger M, Wennauer R, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boomsma DI, Bornstein SR, Bovet P, Brambilla P, Brown MJ, Campbell H, Caulfield MJ, Chakravarti A, Collins R, Collins FS, Crawford DC, Cupples LA, Danesh J, de Faire U, den Ruijter HM, Erbel R, Erdmann J, Eriksson JG, Farrall M, Ferrannini E, Ferrieres J, Ford I, Forouhi NG, Forrester T, Gansevoort RT, Gejman PV, Gieger C, Golay A, Gottesman O, Gudnason V, Gyllensten U, Haas DW, Hall AS, Harris TB, Hattersley AT, Heath AC, Hengstenberg C, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Hovingh GK, Humphries SE, Hunt SC, Hypponen E, Jacobs KB, Jarvelin MR, Jousilahti P, Jula AM, Kaprio J, Kastelein JJ, Kayser M, Kee F, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kooner JS, Kooperberg C, Koskinen S, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimaki T, Lupoli S, Madden PA, Mannisto S, Manunta P, Marette A, Matise TC, McKnight B, Meitinger T, Moll FL, Montgomery GW, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Ouwehand WH, Pasterkamp G, Peters A, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ritchie M, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Sebert S, Sever P, Shuldiner AR, Sinisalo J, Steinthorsdottir V, Stolk RP, Tardif JC, Tonjes A, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Electronic Medical R, Genomics C, Consortium MI, Consortium P, LifeLines Cohort S, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PI, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hayes MG, Hui J, Hunter DJ, Hveem K, Jukema JW, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, Marz W, Melbye M, Moebus S, Munroe PB, Njolstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Perusse L, Peters U, Powell JE, Power C, Quertermous T, Rauramaa R, Reinmaa E, Ridker PM, Rivadeneira F, Rotter JI, Saaristo TE, Saleheen D, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Strauch K, Stumvoll M, Tuomilehto J, Uusitupa M, van der Harst P, Volzke H, Walker M, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Zanen P, Deloukas P, Heid IM, Lindgren CM, Mohlke KL, Speliotes EK, Thorsteinsdottir U, Barroso I, Fox CS, North KE, Strachan DP, Beckmann JS, Berndt SI, Boehnke M, Borecki IB, McCarthy MI, Metspalu A, Stefansson K, Uitterlinden AG, van Duijn CM, Franke L, Willer CJ, Price AL, Lettre G, Loos RJ, Weedon MN, Ingelsson E, O’Connell JR, Abecasis GR, Chasman DI, Goddard ME, Visscher PM, Hirschhorn JN, Frayling TM. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature genetics. 2014;46(11):1173-86. doi: 10.1038/ng.3097. (PubMed ID Number: 25282103; PMCID: PMC4250049).
Xanthakis V, Enserro DM, Murabito JM, Polak JF, Wollert KC, Januzzi JL, Wang TJ, Tofler G, Vasan RS. Ideal cardiovascular health: associations with biomarkers and subclinical disease and impact on incidence of cardiovascular disease in the Framingham offspring study. Circulation. 2014;130(19):1676-83. doi: 10.1161/CIRCULATIONAHA.114.009273. (PubMed ID Number: 25274000).
Xanthakis V, Sullivan LM, Vasan RS, Benjamin EJ, Massaro JM, D’Agostino RB, Sr., Pencina MJ. Assessing the incremental predictive performance of novel biomarkers over standard predictors. Stat Med. 2014;33(15):2577-84. doi: 10.1002/sim.6165. (PubMed ID Number: 24719270; PMCID: PMC4047140).
Xing C, Dupuis J, Cupples L. Performance of statistical methods on CHARGE targeted sequencing data. BMC Genet. 2014;15(1):104. doi: 10.1186/s12863-014-0104-9. (PubMed ID Number: 25277365; PMCID: PMC4197341).
Yao C, Joehanes R, Johnson AD, Huan T, Esko T, Ying S, Freedman JE, Murabito J, Lunetta KL, Metspalu A, Munson PJ, Levy D. Sex- and age-interacting eQTLs in human complex diseases. Hum Mol Genet. 2014;23(7):1947-56. doi: 10.1093/hmg/ddt582. (PubMed ID Number: 24242183; PMCID: PMC3943525).
Yin X, Subramanian S, Hwang SJ, O’Donnell CJ, Fox CS, Courchesne P, Muntendam P, Gordon N, Adourian A, Juhasz P, Larson MG, Levy D. Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative. Arterioscler Thromb Vasc Biol. 2014;34(4):939-45. doi: 10.1161/ATVBAHA.113.302918. (PubMed ID Number: 24526693; PMCID: PMC4061732).
Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, Cooper-Dehoff RM, Gaunt TR, Gieger C, Gong Y, Gorski M, Heard-Costa N, Johnson T, Lamonte MJ, McDonough C, Monda KL, Onland-Moret NC, Nelson CP, O’Connell JR, Ordovas J, Peter I, Peters A, Shaffer J, Shen H, Smith E, Speilotes L, Thomas F, Thorand B, Monique Verschuren WM, Anand SS, Dominiczak A, Davidson KW, Hegele RA, Heid I, Hofker MH, Huggins GS, Illig T, Johnson JA, Kirkland S, Look ARG, Konig W, Langaee TY, McCaffery J, Melander O, Mitchell BD, Munroe P, Murray SS, Papanicolaou G, Redline S, Reilly M, Samani NJ, Schork NJ, Van Der Schouw YT, Shimbo D, Shuldiner AR, Tobin MD, Wijmenga C, Yusuf S, Consortium G, Consortium CAI, Hakonarson H, Lange LA, Demerath EW, Fox CS, North KE, Reiner AP, Keating B, Taylor KC. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Hum Mol Genet. 2014;23(9):2498-510. doi: 10.1093/hmg/ddt626. (PubMed ID Number: 24345515; PMCID: PMC3988452).
Zhang X, Gierman HJ, Levy D, Plump A, Dobrin R, Goring HH, Curran JE, Johnson MP, Blangero J, Kim SK, O’Donnell CJ, Emilsson V, Johnson AD. Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs. BMC genomics. 2014;15:532. doi: 10.1186/1471-2164-15-532. (PubMed ID Number: 24973796; PMCID: PMC4102726).
Zhang X, Johnson AD, Hendricks AE, Hwang SJ, Tanriverdi K, Ganesh SK, Smith NL, Peyser PA, Freedman JE, O’Donnell CJ. Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes. Hum Mol Genet. 2014 Feb 1;23(3):782-95. doi: 10.1093/hmg/ddt461. (PubMed ID Number: 24057673; PMCID: PMC3900869).
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