Manuals of Procedures

Manuals of Procedures

This page contains information geared towards the scientific community, investigators, and potential investigators. The tables list study protocols/manuals for the Framingham Heart Study Generation 3 and Omni 2 Cohorts’ Examination 3, onsite at the Framingham Research Center or offsite at participant homes and/or nursing homes.

These manuals refer to core components of the examination (in order of their administration). Ancillary Studies have not been included.

Onsite Exam Manual

• Informed Consent and Admitting Procedure
• Anthropometrics
• Tech Administered Questionnaires
• Self-Administered Questionnaires
• Observe Performance Hand Grip
• ECG
• Physician Administered Medical History and Blood Pressure
• Neurocognitive Questionnaires
  • Neurocognitive Questionnaire
  • Neurocognitive Questionnaire – Referral Forms
  • Neurocognitive Questionnaire – CERAD, Stroop, Montreal Cognitive, AD8
• Phlebotomy
• Food Frequency Questionnaire
• Exit Interview

Offsite Exam Manual

• Offsite Manual includes:
  • Gen 3 Exam 3 Components-Offsite
  • Scheduling Offsite Visits
  • Preparation for an Off-site Examination
  • Medical History
  • Blood Pressure Measurement & Maximum Inflation Level
  • Weight Offsite Visits
  • Visiting the Cognitively Impaired
  • Nursing Home Chart Review Protocol
  • Offsite Visit Chart Completion
  • Security Measures
  • Using the REDCap Mobile App

Laboratory Manuals

• Pre-Analytical
• Analytical
• Post-Analytical

Genetic Laboratory Manuals

• Lab Culture
• DNA Extraction
• Quality Control

Endpoint Review Manual

• Endpoint-Review

Noninvasive and Biomarker Protocols

• See documentation here.