Gen 3/Omni 2 Exam 4 Collaboration

FHS Guide for Researchers interested in Generation 3 Exam 4 Collaboration

Edition: February 24, 2020

Dear Framingham Heart Study Research Community,
The National Heart, Lung, and Blood Institute (NHLBI) has announced plans to fund a limited clinic exam cycle in the Generation 3 and Omni 2 Cohorts of the Framingham Heart Study (FHS).
The examination is expected to begin on or about January 2, 2022. The exam is intended in part to serve as a platform for additional, independently funded exam components via investigator-initiated grants or other independently funded projects to enrich the exam data collection with additional hypothesis-driven content. The research aims of such exam-related ancillary projects need not be limited to those within the mission of the NHLBI but must be consistent with and/or complement FHS study objectives.
Read more: NOT-HL-19-732

Regarding the NHLBI Epidemiology Digital Forum: There is a statement in the Notice NOT-HL-19-732: “Further information about application submission timing is available on the NHLBI Epidemiology Digital Forum.”

Steps for Interested Researchers:

STEP 1: Review FHS proposal guidance online:

STEP 2: Apply for FHS Review Committees’ approval prior to your submission to any sponsor. Please apply for FHS approval online via the FHS Research Application.

STEP 3: Apply for sponsorship. If you are interested in NIH funding, our Project Officers recommended the following  R01 application dates posted below.
Projections & Power Calculations

Please see below for projections of the numbers of participants for the Gen 3 Exam 4 exam cycle (n=3374), breakdowns by cohort, sex, age group and race/ethnicity, and power calculations for various types of analyses.

 

If you have questions and/or comments, please contact fhs@bu.edu

Thank you,
Framingham Heart Study
Boston University School of Medicine